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Network neighborhood for query Sequence : CERK1_MOUSE

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CERK1_MOUSE
SwissProt Accessions	Q8K4Q7	Gene names	Cerk
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (mCERK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CERK1_HUMAN
θ value	0 (rank : 1)	NC score	0.997655 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT0, Q9BYB3, Q9UGE5	Gene names	CERK, KIAA1646
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (hCERK) (Lipid kinase 4) (LK4).

CERK1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4Q7	Gene names	Cerk
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (mCERK).

CERKL_HUMAN
θ value	8.02596e-49 (rank : 3)	NC score	0.851221 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q49MI3, Q49MH9, Q49MI0, Q49MI1, Q49MI2, Q5DVJ2, Q5DVJ4, Q5DVJ5, Q6UZF6, Q6ZP59	Gene names	CERKL
Domain Architecture	No domain graphic available
Description	Ceramide kinase-like protein.

SPHK2_HUMAN
θ value	1.33526e-19 (rank : 4)	NC score	0.641539 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK2_MOUSE
θ value	1.13037e-18 (rank : 5)	NC score	0.632921 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK1_HUMAN
θ value	5.60996e-18 (rank : 6)	NC score	0.699240 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

MULK_MOUSE
θ value	7.09661e-13 (rank : 7)	NC score	0.578313 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESW4, Q9D087	Gene names	Mulk
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK).

MULK_HUMAN
θ value	6.00763e-12 (rank : 8)	NC score	0.571801 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q53H12, Q75KN1, Q96GC3, Q9NP48	Gene names	MULK, AGK
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK) (HsMuLK) (Acylglycerol kinase) (hAGK).

GPR85_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.016806 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	P60893, Q9JHI6, Q9NPD1	Gene names	GPR85, SREB2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

GPR85_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.016806 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	P60894, Q9JHI6, Q9NPD1	Gene names	Gpr85, Sreb2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

RL3L_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.030132 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q92901	Gene names	RPL3L
Domain Architecture
Description	60S ribosomal protein L3-like.

AP3B1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.013372 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DGKB_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.007695 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	238	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

GP173_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.012499 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	875	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS66	Gene names	GPR173, SREB3
Domain Architecture
Description	Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3).

GP173_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.012548 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	877	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI62, Q4VA66	Gene names	Gpr173, Sreb3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3).

CC040_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.013149 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWU3, Q99KY5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 homolog precursor.

CCAR1_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.008185 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	414	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

Hits sorted by NC score

CERK1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4Q7	Gene names	Cerk
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (mCERK).

CERK1_HUMAN
NC score	0.997655 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT0, Q9BYB3, Q9UGE5	Gene names	CERK, KIAA1646
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (hCERK) (Lipid kinase 4) (LK4).

CERKL_HUMAN
NC score	0.851221 (rank : 3)	θ value	8.02596e-49 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q49MI3, Q49MH9, Q49MI0, Q49MI1, Q49MI2, Q5DVJ2, Q5DVJ4, Q5DVJ5, Q6UZF6, Q6ZP59	Gene names	CERKL
Domain Architecture	No domain graphic available
Description	Ceramide kinase-like protein.

SPHK1_HUMAN
NC score	0.699240 (rank : 4)	θ value	5.60996e-18 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

SPHK2_HUMAN
NC score	0.641539 (rank : 5)	θ value	1.33526e-19 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK2_MOUSE
NC score	0.632921 (rank : 6)	θ value	1.13037e-18 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

MULK_MOUSE
NC score	0.578313 (rank : 7)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESW4, Q9D087	Gene names	Mulk
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK).

MULK_HUMAN
NC score	0.571801 (rank : 8)	θ value	6.00763e-12 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q53H12, Q75KN1, Q96GC3, Q9NP48	Gene names	MULK, AGK
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK) (HsMuLK) (Acylglycerol kinase) (hAGK).

RL3L_HUMAN
NC score	0.030132 (rank : 9)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q92901	Gene names	RPL3L
Domain Architecture
Description	60S ribosomal protein L3-like.

GPR85_HUMAN
NC score	0.016806 (rank : 10)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	P60893, Q9JHI6, Q9NPD1	Gene names	GPR85, SREB2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

GPR85_MOUSE
NC score	0.016806 (rank : 11)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	P60894, Q9JHI6, Q9NPD1	Gene names	Gpr85, Sreb2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

AP3B1_MOUSE
NC score	0.013372 (rank : 12)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CC040_MOUSE
NC score	0.013149 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWU3, Q99KY5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 homolog precursor.

GP173_MOUSE
NC score	0.012548 (rank : 14)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	877	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI62, Q4VA66	Gene names	Gpr173, Sreb3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3).

GP173_HUMAN
NC score	0.012499 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	875	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS66	Gene names	GPR173, SREB3
Domain Architecture
Description	Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3).

CCAR1_MOUSE
NC score	0.008185 (rank : 16)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	414	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

DGKB_HUMAN
NC score	0.007695 (rank : 17)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	238	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).