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Network neighborhood for query Sequence : ARFP2_HUMAN

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ARFP2_HUMAN
SwissProt Accessions	P53365	Gene names	ARFIP2, POR1
Domain Architecture
Description	Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (Protein POR1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARFP2_HUMAN
θ value	9.76035e-180 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P53365	Gene names	ARFIP2, POR1
Domain Architecture
Description	Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (Protein POR1).

ARFP2_MOUSE
θ value	5.35569e-178 (rank : 2)	NC score	0.999502 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K221, Q3U3G6, Q9D7M3	Gene names	Arfip2
Domain Architecture	No domain graphic available
Description	Arfaptin-2 (ADP-ribosylation factor-interacting protein 2).

ARFP1_HUMAN
θ value	3.31004e-111 (rank : 3)	NC score	0.970255 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	P53367, Q9Y2X6	Gene names	ARFIP1
Domain Architecture
Description	Arfaptin-1 (ADP-ribosylation factor-interacting protein 1).

PICK1_HUMAN
θ value	9.59137e-10 (rank : 4)	NC score	0.406378 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	9.59137e-10 (rank : 5)	NC score	0.409124 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

AL2SE_HUMAN
θ value	0.000461057 (rank : 6)	NC score	0.279777 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

AL2SE_MOUSE
θ value	0.00175202 (rank : 7)	NC score	0.269001 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TY65, Q6AXB8, Q6PD23, Q8C0R6, Q9D9S5	Gene names	Als2cr15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein homolog (Ica69-related protein).

ICA69_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.227081 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

ICA69_MOUSE
θ value	0.0193708 (rank : 9)	NC score	0.223714 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

DNJC1_MOUSE
θ value	0.365318 (rank : 10)	NC score	0.049816 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

TBCD4_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.043757 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

PB1_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.040399 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

APOE_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.030672 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	319	Shared Neighborhood Hits	4
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

GRP78_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.016026 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GCP60_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.019560 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

EEA1_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.010346 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1637	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LZTS2_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.018817 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	427	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

CNTN4_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.005856 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	449	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

KCNN2_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.015684 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

TBCD4_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.027185 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

Hits sorted by NC score

ARFP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.76035e-180 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P53365	Gene names	ARFIP2, POR1
Domain Architecture
Description	Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (Protein POR1).

ARFP2_MOUSE
NC score	0.999502 (rank : 2)	θ value	5.35569e-178 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K221, Q3U3G6, Q9D7M3	Gene names	Arfip2
Domain Architecture	No domain graphic available
Description	Arfaptin-2 (ADP-ribosylation factor-interacting protein 2).

ARFP1_HUMAN
NC score	0.970255 (rank : 3)	θ value	3.31004e-111 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	P53367, Q9Y2X6	Gene names	ARFIP1
Domain Architecture
Description	Arfaptin-1 (ADP-ribosylation factor-interacting protein 1).

PICK1_MOUSE
NC score	0.409124 (rank : 4)	θ value	9.59137e-10 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.406378 (rank : 5)	θ value	9.59137e-10 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

AL2SE_HUMAN
NC score	0.279777 (rank : 6)	θ value	0.000461057 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

AL2SE_MOUSE
NC score	0.269001 (rank : 7)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TY65, Q6AXB8, Q6PD23, Q8C0R6, Q9D9S5	Gene names	Als2cr15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein homolog (Ica69-related protein).

ICA69_HUMAN
NC score	0.227081 (rank : 8)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

ICA69_MOUSE
NC score	0.223714 (rank : 9)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

DNJC1_MOUSE
NC score	0.049816 (rank : 10)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

TBCD4_HUMAN
NC score	0.043757 (rank : 11)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

PB1_HUMAN
NC score	0.040399 (rank : 12)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

APOE_MOUSE
NC score	0.030672 (rank : 13)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	319	Shared Neighborhood Hits	4
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

TBCD4_MOUSE
NC score	0.027185 (rank : 14)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

GCP60_HUMAN
NC score	0.019560 (rank : 15)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

LZTS2_HUMAN
NC score	0.018817 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	427	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

GRP78_MOUSE
NC score	0.016026 (rank : 17)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

KCNN2_MOUSE
NC score	0.015684 (rank : 18)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

EEA1_MOUSE
NC score	0.010346 (rank : 19)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	1637	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CNTN4_HUMAN
NC score	0.005856 (rank : 20)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	449	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).