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Network neighborhood for query Sequence : AMPM2_MOUSE

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AMPM2_MOUSE
SwissProt Accessions	O08663	Gene names	Metap2, Mnpep, P67eif2
Domain Architecture
Description	Methionine aminopeptidase 2 (EC 3.4.11.18) (MetAP 2) (Peptidase M 2) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AMPM2_HUMAN
θ value	0 (rank : 1)	NC score	0.997314 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P50579	Gene names	METAP2, MNPEP, P67EIF2
Domain Architecture
Description	Methionine aminopeptidase 2 (EC 3.4.11.18) (MetAP 2) (Peptidase M 2) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2).

AMPM2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O08663	Gene names	Metap2, Mnpep, P67eif2
Domain Architecture
Description	Methionine aminopeptidase 2 (EC 3.4.11.18) (MetAP 2) (Peptidase M 2) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2).

PA2G4_HUMAN
θ value	1.6852e-22 (rank : 3)	NC score	0.686855 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ80, O43846, Q9UM59	Gene names	PA2G4, EBP1
Domain Architecture
Description	Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1).

PA2G4_MOUSE
θ value	1.6852e-22 (rank : 4)	NC score	0.685705 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P50580	Gene names	Pa2g4, Ebp1, Plfap
Domain Architecture
Description	Proliferation-associated protein 2G4 (Proliferation-associated protein 1) (Protein p38-2G4) (Mpp1) (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45).

DGCR8_MOUSE
θ value	2.36792 (rank : 5)	NC score	0.029603 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

CLGN_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.025242 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

ERCC5_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.021914 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

NEST_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.009046 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	1305	Shared Neighborhood Hits	7
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

TCAL5_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.010607 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	806	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CMGA_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.019718 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

PCLO_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.006129 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	2275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TRI56_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.013765 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

XPP1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.031303 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

XPP1_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.031370 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

LMBL3_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.014527 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

MDC1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.006747 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1446	Shared Neighborhood Hits	5
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MY18A_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.001931 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	1989	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PTPRT_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.010723 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.008722 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

Hits sorted by NC score

AMPM2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O08663	Gene names	Metap2, Mnpep, P67eif2
Domain Architecture
Description	Methionine aminopeptidase 2 (EC 3.4.11.18) (MetAP 2) (Peptidase M 2) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2).

AMPM2_HUMAN
NC score	0.997314 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P50579	Gene names	METAP2, MNPEP, P67EIF2
Domain Architecture
Description	Methionine aminopeptidase 2 (EC 3.4.11.18) (MetAP 2) (Peptidase M 2) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2).

PA2G4_HUMAN
NC score	0.686855 (rank : 3)	θ value	1.6852e-22 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ80, O43846, Q9UM59	Gene names	PA2G4, EBP1
Domain Architecture
Description	Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1).

PA2G4_MOUSE
NC score	0.685705 (rank : 4)	θ value	1.6852e-22 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P50580	Gene names	Pa2g4, Ebp1, Plfap
Domain Architecture
Description	Proliferation-associated protein 2G4 (Proliferation-associated protein 1) (Protein p38-2G4) (Mpp1) (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45).

XPP1_MOUSE
NC score	0.031370 (rank : 5)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

XPP1_HUMAN
NC score	0.031303 (rank : 6)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

DGCR8_MOUSE
NC score	0.029603 (rank : 7)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

CLGN_MOUSE
NC score	0.025242 (rank : 8)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

ERCC5_MOUSE
NC score	0.021914 (rank : 9)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

CMGA_HUMAN
NC score	0.019718 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

LMBL3_HUMAN
NC score	0.014527 (rank : 11)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

TRI56_HUMAN
NC score	0.013765 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

PTPRT_HUMAN
NC score	0.010723 (rank : 13)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

TCAL5_HUMAN
NC score	0.010607 (rank : 14)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	806	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NEST_HUMAN
NC score	0.009046 (rank : 15)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	1305	Shared Neighborhood Hits	7
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PTPRT_MOUSE
NC score	0.008722 (rank : 16)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

MDC1_HUMAN
NC score	0.006747 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	1446	Shared Neighborhood Hits	5
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCLO_MOUSE
NC score	0.006129 (rank : 18)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	2275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MY18A_MOUSE
NC score	0.001931 (rank : 19)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1989	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).