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Network neighborhood for query Sequence : ALK1_HUMAN

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ALK1_HUMAN
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ALK1_HUMAN
θ value	1.35638e-80 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

ALK1_MOUSE
θ value	1.08474e-45 (rank : 2)	NC score	0.958277 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

WFDC5_HUMAN
θ value	9.26847e-13 (rank : 3)	NC score	0.757691 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

WFDC3_HUMAN
θ value	3.89403e-11 (rank : 4)	NC score	0.570827 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ELAF_HUMAN
θ value	2.79066e-09 (rank : 5)	NC score	0.742268 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P19957	Gene names	PI3, WAP3, WFDC14
Domain Architecture
Description	Elafin precursor (Elastase-specific inhibitor) (ESI) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) (Protease inhibitor WAP3).

WFDC2_HUMAN
θ value	2.79066e-09 (rank : 6)	NC score	0.644733 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WFD12_HUMAN
θ value	6.87365e-08 (rank : 7)	NC score	0.725317 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWY7, Q5H980, Q9BR31	Gene names	WFDC12, C20orf122, WAP2
Domain Architecture
Description	WAP four-disulfide core domain protein 12 precursor (Putative protease inhibitor WAP12) (Whey acidic protein 2).

WFDC8_HUMAN
θ value	1.43324e-05 (rank : 8)	NC score	0.512662 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

WAP_MOUSE
θ value	1.87187e-05 (rank : 9)	NC score	0.593575 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	P01173, P70230, Q61023	Gene names	Wap
Domain Architecture
Description	Whey acidic protein precursor (WAP).

WFD12_MOUSE
θ value	5.44631e-05 (rank : 10)	NC score	0.572379 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHY3	Gene names	Wfdc12, Swam2
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 12 precursor (Whey acidic protein 2) (Single WAP motif protein 2) (Elafin-like protein II).

EXPI_MOUSE
θ value	0.000602161 (rank : 11)	NC score	0.613751 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P62810, Q62477, Q91VQ6	Gene names	Expi, Wdnm1
Domain Architecture	No domain graphic available
Description	Extracellular peptidase inhibitor precursor (Protein WDNM1).

EPPI_HUMAN
θ value	0.000786445 (rank : 12)	NC score	0.335641 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

EPPI_MOUSE
θ value	0.00134147 (rank : 13)	NC score	0.357675 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

WFDC2_MOUSE
θ value	0.00509761 (rank : 14)	NC score	0.550670 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DAU7	Gene names	Wfdc2, He4
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (WAP domain- containing protein HE4).

MCSP_MOUSE
θ value	0.0193708 (rank : 15)	NC score	0.211766 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

WFDC1_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.289302 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HC57, Q8NC27, Q9HAU1	Gene names	WFDC1, PS20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFDC1_MOUSE
θ value	0.0193708 (rank : 17)	NC score	0.295520 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESH5, Q8R110	Gene names	Wfdc1, Ps20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFDC6_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.327701 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQY6, Q5JYQ4, Q8NFV6	Gene names	WFDC6, C20orf171, WAP6
Domain Architecture
Description	WAP four-disulfide core domain protein 6 precursor (Putative protease inhibitor WAP6).

WFD15_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.452294 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHY4, Q8BVC0	Gene names	Wfdc15, Swam1
Domain Architecture
Description	WAP four-disulfide core domain protein 15 precursor (Single WAP motif protein 1) (Elafin-like protein I).

KALM_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.284985 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

UROL1_MOUSE
θ value	0.0563607 (rank : 21)	NC score	0.167741 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.148923 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	213	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CRIM1_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.056361 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NOTC3_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.024197 (rank : 45)
Query Neighborhood Hits	33	Target Neighborhood Hits	975	Shared Neighborhood Hits	13
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PRG4_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.037404 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ZAN_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.045147 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	808	Shared Neighborhood Hits	16
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DLL3_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.026960 (rank : 43)
Query Neighborhood Hits	33	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

PRG4_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.032452 (rank : 40)
Query Neighborhood Hits	33	Target Neighborhood Hits	624	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SORL_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.021863 (rank : 47)
Query Neighborhood Hits	33	Target Neighborhood Hits	440	Shared Neighborhood Hits	9
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TENA_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.028772 (rank : 42)
Query Neighborhood Hits	33	Target Neighborhood Hits	596	Shared Neighborhood Hits	16
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

DLL3_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.025278 (rank : 44)
Query Neighborhood Hits	33	Target Neighborhood Hits	399	Shared Neighborhood Hits	12
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

SSPO_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.029434 (rank : 41)
Query Neighborhood Hits	33	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SORL_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.022992 (rank : 46)
Query Neighborhood Hits	33	Target Neighborhood Hits	439	Shared Neighborhood Hits	11
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

KR171_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.052022 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.059167 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA56_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.050797 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA58_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.053981 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	324	Shared Neighborhood Hits	12
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LCE1E_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.056521 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.053188 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MCSP_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.058191 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPIT2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.051441 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

SPIT2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.053524 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

SPIT3_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.075123 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

TFPI2_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.055145 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

TFPI2_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.055493 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

WF10A_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.074831 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1F0, Q5TGZ7	Gene names	WFDC10A, C20orf146, WAP10
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 10A precursor (Putative protease inhibitor WAP10A).

WFD13_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.105151 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

Hits sorted by NC score

ALK1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.35638e-80 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

ALK1_MOUSE
NC score	0.958277 (rank : 2)	θ value	1.08474e-45 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

WFDC5_HUMAN
NC score	0.757691 (rank : 3)	θ value	9.26847e-13 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ELAF_HUMAN
NC score	0.742268 (rank : 4)	θ value	2.79066e-09 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P19957	Gene names	PI3, WAP3, WFDC14
Domain Architecture
Description	Elafin precursor (Elastase-specific inhibitor) (ESI) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) (Protease inhibitor WAP3).

WFD12_HUMAN
NC score	0.725317 (rank : 5)	θ value	6.87365e-08 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWY7, Q5H980, Q9BR31	Gene names	WFDC12, C20orf122, WAP2
Domain Architecture
Description	WAP four-disulfide core domain protein 12 precursor (Putative protease inhibitor WAP12) (Whey acidic protein 2).

WFDC2_HUMAN
NC score	0.644733 (rank : 6)	θ value	2.79066e-09 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

EXPI_MOUSE
NC score	0.613751 (rank : 7)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P62810, Q62477, Q91VQ6	Gene names	Expi, Wdnm1
Domain Architecture	No domain graphic available
Description	Extracellular peptidase inhibitor precursor (Protein WDNM1).

WAP_MOUSE
NC score	0.593575 (rank : 8)	θ value	1.87187e-05 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	P01173, P70230, Q61023	Gene names	Wap
Domain Architecture
Description	Whey acidic protein precursor (WAP).

WFD12_MOUSE
NC score	0.572379 (rank : 9)	θ value	5.44631e-05 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHY3	Gene names	Wfdc12, Swam2
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 12 precursor (Whey acidic protein 2) (Single WAP motif protein 2) (Elafin-like protein II).

WFDC3_HUMAN
NC score	0.570827 (rank : 10)	θ value	3.89403e-11 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WFDC2_MOUSE
NC score	0.550670 (rank : 11)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DAU7	Gene names	Wfdc2, He4
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (WAP domain- containing protein HE4).

WFDC8_HUMAN
NC score	0.512662 (rank : 12)	θ value	1.43324e-05 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

WFD15_MOUSE
NC score	0.452294 (rank : 13)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHY4, Q8BVC0	Gene names	Wfdc15, Swam1
Domain Architecture
Description	WAP four-disulfide core domain protein 15 precursor (Single WAP motif protein 1) (Elafin-like protein I).

EPPI_MOUSE
NC score	0.357675 (rank : 14)	θ value	0.00134147 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

EPPI_HUMAN
NC score	0.335641 (rank : 15)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

WFDC6_HUMAN
NC score	0.327701 (rank : 16)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQY6, Q5JYQ4, Q8NFV6	Gene names	WFDC6, C20orf171, WAP6
Domain Architecture
Description	WAP four-disulfide core domain protein 6 precursor (Putative protease inhibitor WAP6).

WFDC1_MOUSE
NC score	0.295520 (rank : 17)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESH5, Q8R110	Gene names	Wfdc1, Ps20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFDC1_HUMAN
NC score	0.289302 (rank : 18)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HC57, Q8NC27, Q9HAU1	Gene names	WFDC1, PS20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

KALM_HUMAN
NC score	0.284985 (rank : 19)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

MCSP_MOUSE
NC score	0.211766 (rank : 20)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

UROL1_MOUSE
NC score	0.167741 (rank : 21)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_HUMAN
NC score	0.148923 (rank : 22)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	213	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WFD13_HUMAN
NC score	0.105151 (rank : 23)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	33	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

SPIT3_HUMAN
NC score	0.075123 (rank : 24)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

WF10A_HUMAN
NC score	0.074831 (rank : 25)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	33	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1F0, Q5TGZ7	Gene names	WFDC10A, C20orf146, WAP10
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 10A precursor (Putative protease inhibitor WAP10A).

KRA53_HUMAN
NC score	0.059167 (rank : 26)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

MCSP_HUMAN
NC score	0.058191 (rank : 27)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LCE1E_HUMAN
NC score	0.056521 (rank : 28)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CRIM1_HUMAN
NC score	0.056361 (rank : 29)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

TFPI2_MOUSE
NC score	0.055493 (rank : 30)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	33	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

TFPI2_HUMAN
NC score	0.055145 (rank : 31)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

KRA58_HUMAN
NC score	0.053981 (rank : 32)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	324	Shared Neighborhood Hits	12
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SPIT2_MOUSE
NC score	0.053524 (rank : 33)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

LCE1F_HUMAN
NC score	0.053188 (rank : 34)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

KR171_HUMAN
NC score	0.052022 (rank : 35)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

SPIT2_HUMAN
NC score	0.051441 (rank : 36)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

KRA56_HUMAN
NC score	0.050797 (rank : 37)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

ZAN_MOUSE
NC score	0.045147 (rank : 38)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	808	Shared Neighborhood Hits	16
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

PRG4_HUMAN
NC score	0.037404 (rank : 39)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
NC score	0.032452 (rank : 40)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	624	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SSPO_MOUSE
NC score	0.029434 (rank : 41)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TENA_MOUSE
NC score	0.028772 (rank : 42)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	596	Shared Neighborhood Hits	16
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

DLL3_HUMAN
NC score	0.026960 (rank : 43)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
NC score	0.025278 (rank : 44)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	399	Shared Neighborhood Hits	12
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NOTC3_MOUSE
NC score	0.024197 (rank : 45)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	975	Shared Neighborhood Hits	13
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SORL_MOUSE
NC score	0.022992 (rank : 46)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	439	Shared Neighborhood Hits	11
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SORL_HUMAN
NC score	0.021863 (rank : 47)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	440	Shared Neighborhood Hits	9
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).