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Network neighborhood for query Sequence : VANG2_HUMAN

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VANG2_HUMAN
SwissProt Accessions	Q9ULK5	Gene names	VANGL2, KIAA1215, STB1
Domain Architecture
Description	Vang-like protein 2 (Van Gogh-like protein 2) (Strabismus 1) (Loop- tail protein 1 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VANG1_HUMAN
θ value	0 (rank : 1)	NC score	0.994704 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAA9, Q86WG8, Q8N559	Gene names	VANGL1, STB2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Strabismus 2) (Loop- tail protein 2 homolog) (LPP2).

VANG2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULK5	Gene names	VANGL2, KIAA1215, STB1
Domain Architecture
Description	Vang-like protein 2 (Van Gogh-like protein 2) (Strabismus 1) (Loop- tail protein 1 homolog).

VANG2_MOUSE
θ value	0 (rank : 3)	NC score	0.999960 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZD4, Q923Z8	Gene names	Vangl2, Lpp1, Ltap
Domain Architecture
Description	Vang-like protein 2 (Van Gogh-like protein 2) (Loop-tail-associated protein) (Loop-tail protein 1).

VANG1_MOUSE
θ value	2.40406e-178 (rank : 4)	NC score	0.995486 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Z96, Q8QZT3	Gene names	Vangl1, Lpp2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Loop-tail protein 2).

TRI16_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.029121 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

APLP2_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.029119 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

APLP2_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.030636 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

CHST4_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.016664 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCG5, Q8IV46, Q9Y5R3	Gene names	CHST4
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 2) (GlcNAc6ST-2) (High endothelial cells N- acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 3) (GST-3).

EXOC1_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.027385 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

NEK2_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.001682 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	908	Shared Neighborhood Hits	3
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

EXOC1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.025177 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

PIGC_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.025609 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q92535, O14491	Gene names	PIGC, GPI2
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C).

HXK3_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.009212 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

TRI16_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.017109 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

Hits sorted by NC score

VANG2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULK5	Gene names	VANGL2, KIAA1215, STB1
Domain Architecture
Description	Vang-like protein 2 (Van Gogh-like protein 2) (Strabismus 1) (Loop- tail protein 1 homolog).

VANG2_MOUSE
NC score	0.999960 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZD4, Q923Z8	Gene names	Vangl2, Lpp1, Ltap
Domain Architecture
Description	Vang-like protein 2 (Van Gogh-like protein 2) (Loop-tail-associated protein) (Loop-tail protein 1).

VANG1_MOUSE
NC score	0.995486 (rank : 3)	θ value	2.40406e-178 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Z96, Q8QZT3	Gene names	Vangl1, Lpp2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Loop-tail protein 2).

VANG1_HUMAN
NC score	0.994704 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAA9, Q86WG8, Q8N559	Gene names	VANGL1, STB2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Strabismus 2) (Loop- tail protein 2 homolog) (LPP2).

APLP2_MOUSE
NC score	0.030636 (rank : 5)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

TRI16_HUMAN
NC score	0.029121 (rank : 6)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

APLP2_HUMAN
NC score	0.029119 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

EXOC1_HUMAN
NC score	0.027385 (rank : 8)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

PIGC_HUMAN
NC score	0.025609 (rank : 9)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q92535, O14491	Gene names	PIGC, GPI2
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C).

EXOC1_MOUSE
NC score	0.025177 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

TRI16_MOUSE
NC score	0.017109 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

CHST4_HUMAN
NC score	0.016664 (rank : 12)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCG5, Q8IV46, Q9Y5R3	Gene names	CHST4
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 2) (GlcNAc6ST-2) (High endothelial cells N- acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 3) (GST-3).

HXK3_MOUSE
NC score	0.009212 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

NEK2_HUMAN
NC score	0.001682 (rank : 14)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	908	Shared Neighborhood Hits	3
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).