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Network neighborhood for query Sequence : TPH2_MOUSE

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TPH2_MOUSE
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPH1_HUMAN
θ value	0 (rank : 1)	NC score	0.996424 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
θ value	0 (rank : 2)	NC score	0.996237 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_HUMAN
θ value	0 (rank : 3)	NC score	0.999261 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

PH4H_MOUSE
θ value	2.689e-137 (rank : 5)	NC score	0.987213 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_HUMAN
θ value	2.97304e-136 (rank : 6)	NC score	0.986975 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TY3H_MOUSE
θ value	1.0968e-122 (rank : 7)	NC score	0.982076 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_HUMAN
θ value	4.31301e-119 (rank : 8)	NC score	0.980452 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

EMR1_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.021312 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	382	Shared Neighborhood Hits	5
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

MTMRD_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.025718 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CU013_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.023946 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

ITIH2_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.013719 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

CF152_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.013793 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	704	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF152_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.016705 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	597	Shared Neighborhood Hits	5
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

FACD2_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.010461 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

GGLO_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.023005 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

Hits sorted by NC score

TPH2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_HUMAN
NC score	0.999261 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH1_HUMAN
NC score	0.996424 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
NC score	0.996237 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

PH4H_MOUSE
NC score	0.987213 (rank : 5)	θ value	2.689e-137 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_HUMAN
NC score	0.986975 (rank : 6)	θ value	2.97304e-136 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TY3H_MOUSE
NC score	0.982076 (rank : 7)	θ value	1.0968e-122 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_HUMAN
NC score	0.980452 (rank : 8)	θ value	4.31301e-119 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

MTMRD_HUMAN
NC score	0.025718 (rank : 9)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CU013_HUMAN
NC score	0.023946 (rank : 10)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

GGLO_MOUSE
NC score	0.023005 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

EMR1_HUMAN
NC score	0.021312 (rank : 12)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	382	Shared Neighborhood Hits	5
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CF152_MOUSE
NC score	0.016705 (rank : 13)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	597	Shared Neighborhood Hits	5
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CF152_HUMAN
NC score	0.013793 (rank : 14)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	704	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

ITIH2_MOUSE
NC score	0.013719 (rank : 15)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

FACD2_HUMAN
NC score	0.010461 (rank : 16)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).