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Network neighborhood for query Sequence : TGM4_HUMAN

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TGM4_HUMAN
SwissProt Accessions	P49221, Q16707, Q96QN4	Gene names	TGM4
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Transglutaminase-4) (TGase-4) (Prostate transglutaminase) (TGP) (TG(P)) (Prostate-specific transglutaminase) (Fibrinoligase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TGM4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P49221, Q16707, Q96QN4	Gene names	TGM4
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Transglutaminase-4) (TGase-4) (Prostate transglutaminase) (TGP) (TG(P)) (Prostate-specific transglutaminase) (Fibrinoligase).

TGM1_HUMAN
θ value	4.74654e-134 (rank : 2)	NC score	0.985133 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P22735	Gene names	TGM1, KTG
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

TGM1_MOUSE
θ value	8.09639e-134 (rank : 3)	NC score	0.985131 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLF6, Q8R0T9	Gene names	Tgm1
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

TGM7_HUMAN
θ value	1.81207e-117 (rank : 4)	NC score	0.984120 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PF1	Gene names	TGM7
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase Z (EC 2.3.2.13) (TGase Z) (TGZ) (TG(Z)) (Transglutaminase 7).

TGM3L_HUMAN
θ value	5.27232e-117 (rank : 5)	NC score	0.984320 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	O95932, Q5JXU4, Q5JXU5, Q719M2, Q719M3, Q9Y4U8	Gene names	TGM6, TGM3L
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 6 (EC 2.3.2.13) (Transglutaminase-3-like) (TGase-3-like) (Transglutaminase Y).

F13A_MOUSE
θ value	3.91003e-112 (rank : 6)	NC score	0.979513 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH61, Q3TNF9, Q8BIP2	Gene names	F13a1, F13a
Domain Architecture	No domain graphic available
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

F13A_HUMAN
θ value	1.25781e-110 (rank : 7)	NC score	0.979445 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P00488, Q8N6X2, Q96P24	Gene names	F13A1, F13A
Domain Architecture
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

TGM5_MOUSE
θ value	3.65967e-110 (rank : 8)	NC score	0.980519 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).

TGM3_HUMAN
θ value	2.6227e-108 (rank : 9)	NC score	0.981583 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q08188, O95933	Gene names	TGM3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

TGM3_MOUSE
θ value	1.69998e-107 (rank : 10)	NC score	0.980982 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q08189	Gene names	Tgm3, Tgase3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

TGM5_HUMAN
θ value	2.89973e-107 (rank : 11)	NC score	0.979797 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

TGM2_MOUSE
θ value	4.48402e-100 (rank : 12)	NC score	0.978639 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P21981, O88901, Q9R1F7	Gene names	Tgm2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2).

TGM2_HUMAN
θ value	1.70393e-99 (rank : 13)	NC score	0.978840 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P21980, Q16436, Q9BTN7, Q9UH35	Gene names	TGM2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2) (TGase- H).

EPB42_HUMAN
θ value	8.81223e-72 (rank : 14)	NC score	0.960803 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P16452	Gene names	EPB42, E42P
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

EPB42_MOUSE
θ value	3.34864e-71 (rank : 15)	NC score	0.959392 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P49222	Gene names	Epb42, Epb4.2
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

PCDA5_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.001136 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

AT2A3_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.003727 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

MK15_HUMAN
θ value	5.27518 (rank : 18)	NC score	-0.001893 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	1038	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

XCR1_HUMAN
θ value	5.27518 (rank : 19)	NC score	-0.000005 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	711	Shared Neighborhood Hits	3
SwissProt Accessions	P46094	Gene names	XCR1, CCXCR1, GPR5
Domain Architecture
Description	Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactin receptor) (G-protein coupled receptor 5).

BYST_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.009972 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q13895, Q6P5W4, Q86W44, Q96IP8	Gene names	BYSL
Domain Architecture
Description	Bystin.

CYTL1_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.018478 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR1	Gene names	CYTL1, C4orf4
Domain Architecture	No domain graphic available
Description	Cytokine-like protein 1 precursor (Protein C17).

EPHA1_HUMAN
θ value	6.88961 (rank : 22)	NC score	-0.001268 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	6.88961 (rank : 23)	NC score	-0.001179 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	958	Shared Neighborhood Hits	4
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

PK1L1_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.008533 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

Hits sorted by NC score

TGM4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P49221, Q16707, Q96QN4	Gene names	TGM4
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Transglutaminase-4) (TGase-4) (Prostate transglutaminase) (TGP) (TG(P)) (Prostate-specific transglutaminase) (Fibrinoligase).

TGM1_HUMAN
NC score	0.985133 (rank : 2)	θ value	4.74654e-134 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P22735	Gene names	TGM1, KTG
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

TGM1_MOUSE
NC score	0.985131 (rank : 3)	θ value	8.09639e-134 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLF6, Q8R0T9	Gene names	Tgm1
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

TGM3L_HUMAN
NC score	0.984320 (rank : 4)	θ value	5.27232e-117 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	O95932, Q5JXU4, Q5JXU5, Q719M2, Q719M3, Q9Y4U8	Gene names	TGM6, TGM3L
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 6 (EC 2.3.2.13) (Transglutaminase-3-like) (TGase-3-like) (Transglutaminase Y).

TGM7_HUMAN
NC score	0.984120 (rank : 5)	θ value	1.81207e-117 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PF1	Gene names	TGM7
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase Z (EC 2.3.2.13) (TGase Z) (TGZ) (TG(Z)) (Transglutaminase 7).

TGM3_HUMAN
NC score	0.981583 (rank : 6)	θ value	2.6227e-108 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q08188, O95933	Gene names	TGM3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

TGM3_MOUSE
NC score	0.980982 (rank : 7)	θ value	1.69998e-107 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q08189	Gene names	Tgm3, Tgase3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

TGM5_MOUSE
NC score	0.980519 (rank : 8)	θ value	3.65967e-110 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).

TGM5_HUMAN
NC score	0.979797 (rank : 9)	θ value	2.89973e-107 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

F13A_MOUSE
NC score	0.979513 (rank : 10)	θ value	3.91003e-112 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH61, Q3TNF9, Q8BIP2	Gene names	F13a1, F13a
Domain Architecture	No domain graphic available
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

F13A_HUMAN
NC score	0.979445 (rank : 11)	θ value	1.25781e-110 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P00488, Q8N6X2, Q96P24	Gene names	F13A1, F13A
Domain Architecture
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

TGM2_HUMAN
NC score	0.978840 (rank : 12)	θ value	1.70393e-99 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P21980, Q16436, Q9BTN7, Q9UH35	Gene names	TGM2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2) (TGase- H).

TGM2_MOUSE
NC score	0.978639 (rank : 13)	θ value	4.48402e-100 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P21981, O88901, Q9R1F7	Gene names	Tgm2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2).

EPB42_HUMAN
NC score	0.960803 (rank : 14)	θ value	8.81223e-72 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P16452	Gene names	EPB42, E42P
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

EPB42_MOUSE
NC score	0.959392 (rank : 15)	θ value	3.34864e-71 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P49222	Gene names	Epb42, Epb4.2
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

CYTL1_HUMAN
NC score	0.018478 (rank : 16)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR1	Gene names	CYTL1, C4orf4
Domain Architecture	No domain graphic available
Description	Cytokine-like protein 1 precursor (Protein C17).

BYST_HUMAN
NC score	0.009972 (rank : 17)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q13895, Q6P5W4, Q86W44, Q96IP8	Gene names	BYSL
Domain Architecture
Description	Bystin.

PK1L1_HUMAN
NC score	0.008533 (rank : 18)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

AT2A3_HUMAN
NC score	0.003727 (rank : 19)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

PCDA5_HUMAN
NC score	0.001136 (rank : 20)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

XCR1_HUMAN
NC score	-0.000005 (rank : 21)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	711	Shared Neighborhood Hits	3
SwissProt Accessions	P46094	Gene names	XCR1, CCXCR1, GPR5
Domain Architecture
Description	Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactin receptor) (G-protein coupled receptor 5).

EPHA1_MOUSE
NC score	-0.001179 (rank : 22)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	958	Shared Neighborhood Hits	4
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	-0.001268 (rank : 23)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MK15_HUMAN
NC score	-0.001893 (rank : 24)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	1038	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).