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Network neighborhood for query Sequence : T23O_HUMAN

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T23O_HUMAN
SwissProt Accessions	P48775	Gene names	TDO2, TDO
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

T23O_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P48775	Gene names	TDO2, TDO
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

T23O_MOUSE
θ value	0 (rank : 2)	NC score	0.987731 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

ARY2_MOUSE
θ value	0.0563607 (rank : 3)	NC score	0.078901 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P50295	Gene names	Nat2, Aac2
Domain Architecture
Description	Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2).

GCC2_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.029611 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1558	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.029624 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	1559	Shared Neighborhood Hits	9
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ARY1_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.071880 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P18440, O15159, O15300	Gene names	NAT1, AAC1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Arylamine N-acetyltransferase, monomorphic) (MNAT) (N- acetyltransferase type 1) (NAT-1).

RBCC1_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.036586 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1023	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

ADEC1_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.011871 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CENPJ_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.027179 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	721	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

GOGA1_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.014365 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1222	Shared Neighborhood Hits	7
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

K0555_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.020030 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	880	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

NUDC_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.015857 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y266, Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6	Gene names	NUDC
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog).

POLK_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.022573 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLK_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.021986 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

Hits sorted by NC score

T23O_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P48775	Gene names	TDO2, TDO
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

T23O_MOUSE
NC score	0.987731 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

ARY2_MOUSE
NC score	0.078901 (rank : 3)	θ value	0.0563607 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P50295	Gene names	Nat2, Aac2
Domain Architecture
Description	Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2).

ARY1_HUMAN
NC score	0.071880 (rank : 4)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P18440, O15159, O15300	Gene names	NAT1, AAC1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Arylamine N-acetyltransferase, monomorphic) (MNAT) (N- acetyltransferase type 1) (NAT-1).

RBCC1_HUMAN
NC score	0.036586 (rank : 5)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1023	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBP24_HUMAN
NC score	0.029624 (rank : 6)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1559	Shared Neighborhood Hits	9
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.029611 (rank : 7)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	1558	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CENPJ_HUMAN
NC score	0.027179 (rank : 8)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	721	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

POLK_HUMAN
NC score	0.022573 (rank : 9)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLK_MOUSE
NC score	0.021986 (rank : 10)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

K0555_HUMAN
NC score	0.020030 (rank : 11)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	880	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

NUDC_HUMAN
NC score	0.015857 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y266, Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6	Gene names	NUDC
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog).

GOGA1_HUMAN
NC score	0.014365 (rank : 13)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	1222	Shared Neighborhood Hits	7
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

ADEC1_MOUSE
NC score	0.011871 (rank : 14)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).