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Network neighborhood for query Sequence : SECR_MOUSE

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SECR_MOUSE
SwissProt Accessions	Q08535	Gene names	Sct
Domain Architecture
Description	Secretin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SECR_MOUSE
θ value	8.00737e-57 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q08535	Gene names	Sct
Domain Architecture
Description	Secretin precursor.

SECR_HUMAN
θ value	1.74391e-19 (rank : 2)	NC score	0.892793 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P09683	Gene names	SCT
Domain Architecture
Description	Secretin precursor.

PACA_MOUSE
θ value	0.00509761 (rank : 3)	NC score	0.386964 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	O70176	Gene names	Adcyap1, Pacap
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

PACA_HUMAN
θ value	0.0252991 (rank : 4)	NC score	0.364344 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P18509	Gene names	ADCYAP1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

VIP_MOUSE
θ value	0.0330416 (rank : 5)	NC score	0.331646 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P32648, Q9D2Z7, Q9QUN1	Gene names	Vip
Domain Architecture	No domain graphic available
Description	VIP peptides precursor [Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

VIP_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.320730 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P01282, Q96QK3	Gene names	VIP
Domain Architecture
Description	VIP peptides precursor [Contains: Intestinal peptide PHV-42; Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

SLIB_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.243200 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P16043	Gene names	Ghrh
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH).

WNK1_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.010431 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1158	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

SLIB_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.200782 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01286	Gene names	GHRH, GHRF
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin).

GLUC_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.140345 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P01275	Gene names	GCG
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GLUC_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.139389 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P55095, Q3UFE9	Gene names	Gcg
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GIP_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.045296 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P48756	Gene names	Gip
Domain Architecture
Description	Gastric inhibitory polypeptide precursor (GIP) (Glucose-dependent insulinotropic polypeptide).

TAU_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.015655 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

Hits sorted by NC score

SECR_MOUSE
NC score	0.999962 (rank : 1)	θ value	8.00737e-57 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q08535	Gene names	Sct
Domain Architecture
Description	Secretin precursor.

SECR_HUMAN
NC score	0.892793 (rank : 2)	θ value	1.74391e-19 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P09683	Gene names	SCT
Domain Architecture
Description	Secretin precursor.

PACA_MOUSE
NC score	0.386964 (rank : 3)	θ value	0.00509761 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	O70176	Gene names	Adcyap1, Pacap
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

PACA_HUMAN
NC score	0.364344 (rank : 4)	θ value	0.0252991 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P18509	Gene names	ADCYAP1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

VIP_MOUSE
NC score	0.331646 (rank : 5)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P32648, Q9D2Z7, Q9QUN1	Gene names	Vip
Domain Architecture	No domain graphic available
Description	VIP peptides precursor [Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

VIP_HUMAN
NC score	0.320730 (rank : 6)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P01282, Q96QK3	Gene names	VIP
Domain Architecture
Description	VIP peptides precursor [Contains: Intestinal peptide PHV-42; Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

SLIB_MOUSE
NC score	0.243200 (rank : 7)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P16043	Gene names	Ghrh
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH).

SLIB_HUMAN
NC score	0.200782 (rank : 8)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01286	Gene names	GHRH, GHRF
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin).

GLUC_HUMAN
NC score	0.140345 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P01275	Gene names	GCG
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GLUC_MOUSE
NC score	0.139389 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P55095, Q3UFE9	Gene names	Gcg
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GIP_MOUSE
NC score	0.045296 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P48756	Gene names	Gip
Domain Architecture
Description	Gastric inhibitory polypeptide precursor (GIP) (Glucose-dependent insulinotropic polypeptide).

TAU_HUMAN
NC score	0.015655 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WNK1_HUMAN
NC score	0.010431 (rank : 13)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	1158	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).