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Network neighborhood for query Sequence : RPC11_HUMAN

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RPC11_HUMAN
SwissProt Accessions	Q9Y2Y1, Q96S35	Gene names	POLR3K, RPC11
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RPC11_HUMAN
θ value	3.03575e-64 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2Y1, Q96S35	Gene names	POLR3K, RPC11
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11).

RPC11_MOUSE
θ value	2.56992e-63 (rank : 2)	NC score	0.998453 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CQZ7, Q9D1U1	Gene names	Polr3k
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit).

RPB9_HUMAN
θ value	7.59969e-07 (rank : 3)	NC score	0.526673 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P36954, Q6NW05	Gene names	POLR2I
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

RPB9_MOUSE
θ value	7.59969e-07 (rank : 4)	NC score	0.526673 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P60898	Gene names	Polr2i
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

TCEA1_HUMAN
θ value	1.09739e-05 (rank : 5)	NC score	0.475329 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	P23193, Q15563, Q6FG87	Gene names	TCEA1, TFIIS
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

TCEA1_MOUSE
θ value	1.09739e-05 (rank : 6)	NC score	0.478742 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P10711, P10712, P23713	Gene names	Tcea1, Tceat
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

TCEA3_HUMAN
θ value	1.43324e-05 (rank : 7)	NC score	0.477209 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	O75764	Gene names	TCEA3, TFIISH
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

TCEA3_MOUSE
θ value	1.43324e-05 (rank : 8)	NC score	0.477086 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	P23881, O88710, Q9CTZ8, Q9DCZ5	Gene names	Tcea3, Tfiish
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

TCEA2_HUMAN
θ value	3.19293e-05 (rank : 9)	NC score	0.468143 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

TCEA2_MOUSE
θ value	5.44631e-05 (rank : 10)	NC score	0.472715 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QVN7, O08667	Gene names	Tcea2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Protein S-II-T1) (Transcription elongation factor TFIIS.l).

RPA12_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.321249 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q791N7	Gene names	Znrd1, Rpa12
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I subunit 12 (EC 2.7.7.6) (Nuclear RNA polymerase I small-specific subunit Rpa12) (Zinc ribbon domain- containing protein 1).

RPA12_HUMAN
θ value	0.0113563 (rank : 12)	NC score	0.324470 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P1U0	Gene names	ZNRD1, RPA12
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I subunit 12 (EC 2.7.7.6) (Nuclear RNA polymerase I small-specific subunit Rpa12) (Zinc ribbon domain- containing protein 1).

PRKN2_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.090596 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.073020 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

NUD12_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.032011 (rank : 20)
Query Neighborhood Hits	16	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.029787 (rank : 21)
Query Neighborhood Hits	16	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CRSP7_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.124446 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

DIDO1_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.056590 (rank : 19)
Query Neighborhood Hits	16	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.057423 (rank : 18)
Query Neighborhood Hits	16	Target Neighborhood Hits	388	Shared Neighborhood Hits	6
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ELOA1_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.060333 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

PHF3_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.118753 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

Hits sorted by NC score

RPC11_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.03575e-64 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2Y1, Q96S35	Gene names	POLR3K, RPC11
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11).

RPC11_MOUSE
NC score	0.998453 (rank : 2)	θ value	2.56992e-63 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CQZ7, Q9D1U1	Gene names	Polr3k
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit).

RPB9_HUMAN
NC score	0.526673 (rank : 3)	θ value	7.59969e-07 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P36954, Q6NW05	Gene names	POLR2I
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

RPB9_MOUSE
NC score	0.526673 (rank : 4)	θ value	7.59969e-07 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P60898	Gene names	Polr2i
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

TCEA1_MOUSE
NC score	0.478742 (rank : 5)	θ value	1.09739e-05 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P10711, P10712, P23713	Gene names	Tcea1, Tceat
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

TCEA3_HUMAN
NC score	0.477209 (rank : 6)	θ value	1.43324e-05 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	O75764	Gene names	TCEA3, TFIISH
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

TCEA3_MOUSE
NC score	0.477086 (rank : 7)	θ value	1.43324e-05 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	P23881, O88710, Q9CTZ8, Q9DCZ5	Gene names	Tcea3, Tfiish
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

TCEA1_HUMAN
NC score	0.475329 (rank : 8)	θ value	1.09739e-05 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	P23193, Q15563, Q6FG87	Gene names	TCEA1, TFIIS
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

TCEA2_MOUSE
NC score	0.472715 (rank : 9)	θ value	5.44631e-05 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QVN7, O08667	Gene names	Tcea2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Protein S-II-T1) (Transcription elongation factor TFIIS.l).

TCEA2_HUMAN
NC score	0.468143 (rank : 10)	θ value	3.19293e-05 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

RPA12_HUMAN
NC score	0.324470 (rank : 11)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P1U0	Gene names	ZNRD1, RPA12
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I subunit 12 (EC 2.7.7.6) (Nuclear RNA polymerase I small-specific subunit Rpa12) (Zinc ribbon domain- containing protein 1).

RPA12_MOUSE
NC score	0.321249 (rank : 12)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q791N7	Gene names	Znrd1, Rpa12
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I subunit 12 (EC 2.7.7.6) (Nuclear RNA polymerase I small-specific subunit Rpa12) (Zinc ribbon domain- containing protein 1).

CRSP7_HUMAN
NC score	0.124446 (rank : 13)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

PHF3_HUMAN
NC score	0.118753 (rank : 14)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	16	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PRKN2_MOUSE
NC score	0.090596 (rank : 15)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
NC score	0.073020 (rank : 16)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

ELOA1_MOUSE
NC score	0.060333 (rank : 17)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	16	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ELOA1_HUMAN
NC score	0.057423 (rank : 18)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	16	Target Neighborhood Hits	388	Shared Neighborhood Hits	6
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

DIDO1_HUMAN
NC score	0.056590 (rank : 19)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	16	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NUD12_HUMAN
NC score	0.032011 (rank : 20)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
NC score	0.029787 (rank : 21)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).