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Network neighborhood for query Sequence : PSL4_HUMAN

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PSL4_HUMAN
SwissProt Accessions	Q8TCT6, Q8TAU4, Q96DD9	Gene names	SPPL3, PSL4
Domain Architecture
Description	Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3 protein) (Intramembrane protease 2) (IMP2) (Presenilin-like protein 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSL4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT6, Q8TAU4, Q96DD9	Gene names	SPPL3, PSL4
Domain Architecture
Description	Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3 protein) (Intramembrane protease 2) (IMP2) (Presenilin-like protein 4).

PSL4_MOUSE
θ value	3.82926e-184 (rank : 2)	NC score	0.999695 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CUS9, Q8R597	Gene names	Sppl3, Psl4, Usmg3
Domain Architecture
Description	Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3 protein) (Intramembrane protease 2) (IMP2) (Presenilin-like protein 4).

HM13_HUMAN
θ value	5.42112e-21 (rank : 4)	NC score	0.746600 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT9, Q540H8, Q5JWP2, Q5JWP3, Q5JWP4, Q5JWP5, Q7Z4F2, Q86Y35, Q95H87, Q9H110, Q9H111	Gene names	HM13, H13, IMP1, PSL3, SPP
Domain Architecture
Description	Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal peptide peptidase) (Presenilin-like protein 3) (hIMP1 protein).

HM13_MOUSE
θ value	1.13037e-18 (rank : 5)	NC score	0.735261 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8V0, O19444, Q542R3, Q811Z6, Q9CQA4, Q9CSK9	Gene names	Hm13, H13, Psl3
Domain Architecture
Description	Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal peptide peptidase) (Presenilin-like protein 3).

PSL2_HUMAN
θ value	4.29542e-18 (rank : 6)	NC score	0.697969 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT8, Q8TAW1, Q96SZ8	Gene names	SPPL2A, PSL2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (Protein SPP-like 2A) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

PSL2_MOUSE
θ value	1.63225e-17 (rank : 7)	NC score	0.696327 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJF9, Q8R354	Gene names	Sppl2a, Psl2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (SPP-like 2A protein) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

PSL1_HUMAN
θ value	1.99529e-15 (rank : 8)	NC score	0.559004 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

Hits sorted by NC score

PSL4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT6, Q8TAU4, Q96DD9	Gene names	SPPL3, PSL4
Domain Architecture
Description	Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3 protein) (Intramembrane protease 2) (IMP2) (Presenilin-like protein 4).

PSL4_MOUSE
NC score	0.999695 (rank : 2)	θ value	3.82926e-184 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CUS9, Q8R597	Gene names	Sppl3, Psl4, Usmg3
Domain Architecture
Description	Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3 protein) (Intramembrane protease 2) (IMP2) (Presenilin-like protein 4).

HM13_HUMAN
NC score	0.746600 (rank : 3)	θ value	5.42112e-21 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT9, Q540H8, Q5JWP2, Q5JWP3, Q5JWP4, Q5JWP5, Q7Z4F2, Q86Y35, Q95H87, Q9H110, Q9H111	Gene names	HM13, H13, IMP1, PSL3, SPP
Domain Architecture
Description	Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal peptide peptidase) (Presenilin-like protein 3) (hIMP1 protein).

HM13_MOUSE
NC score	0.735261 (rank : 4)	θ value	1.13037e-18 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8V0, O19444, Q542R3, Q811Z6, Q9CQA4, Q9CSK9	Gene names	Hm13, H13, Psl3
Domain Architecture
Description	Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal peptide peptidase) (Presenilin-like protein 3).

PSL2_HUMAN
NC score	0.697969 (rank : 6)	θ value	4.29542e-18 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT8, Q8TAW1, Q96SZ8	Gene names	SPPL2A, PSL2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (Protein SPP-like 2A) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

PSL2_MOUSE
NC score	0.696327 (rank : 7)	θ value	1.63225e-17 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJF9, Q8R354	Gene names	Sppl2a, Psl2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (SPP-like 2A protein) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

PSL1_HUMAN
NC score	0.559004 (rank : 8)	θ value	1.99529e-15 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).