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Network neighborhood for query Sequence : PRPS3_HUMAN

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PRPS3_HUMAN
SwissProt Accessions	P21108	Gene names	PRPS1L1, PRPS3
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase III (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase III) (PRS-III) (Phosphoribosyl pyrophosphate synthetase 1-like 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRPS3_HUMAN
θ value	2.17438e-179 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21108	Gene names	PRPS1L1, PRPS3
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase III (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase III) (PRS-III) (Phosphoribosyl pyrophosphate synthetase 1-like 1).

PRPS1_HUMAN
θ value	5.93515e-169 (rank : 2)	NC score	0.999457 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P60891, P09329	Gene names	PRPS1
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) (PPRibP).

PRPS1_MOUSE
θ value	1.72687e-168 (rank : 3)	NC score	0.999485 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D7G0	Gene names	Prps1
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PRS-I).

PRPS2_MOUSE
θ value	3.37019e-164 (rank : 4)	NC score	0.999287 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CS42, Q9CZA9	Gene names	Prps2
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase II (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase II) (PRS-II).

PRPS2_HUMAN
θ value	4.40161e-164 (rank : 5)	NC score	0.999176 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P11908, Q15245	Gene names	PRPS2
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase II (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) (PPRibP).

KPRB_HUMAN
θ value	3.82246e-75 (rank : 6)	NC score	0.959385 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O60256	Gene names	PRPSAP2
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPP synthetase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41).

KPRB_MOUSE
θ value	4.22625e-74 (rank : 7)	NC score	0.958502 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R574	Gene names	Prpsap2
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPP synthetase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41).

KPRA_HUMAN
θ value	3.70236e-70 (rank : 8)	NC score	0.956061 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q14558, Q96H06	Gene names	PRPSAP1
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPP synthetase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP39).

KPRA_MOUSE
θ value	6.31527e-70 (rank : 9)	NC score	0.955917 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0M1	Gene names	Prpsap1
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPP synthetase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP39).

ZEP1_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.008967 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1036	Shared Neighborhood Hits	5
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

Hits sorted by NC score

PRPS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.17438e-179 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21108	Gene names	PRPS1L1, PRPS3
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase III (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase III) (PRS-III) (Phosphoribosyl pyrophosphate synthetase 1-like 1).

PRPS1_MOUSE
NC score	0.999485 (rank : 2)	θ value	1.72687e-168 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D7G0	Gene names	Prps1
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PRS-I).

PRPS1_HUMAN
NC score	0.999457 (rank : 3)	θ value	5.93515e-169 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P60891, P09329	Gene names	PRPS1
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) (PPRibP).

PRPS2_MOUSE
NC score	0.999287 (rank : 4)	θ value	3.37019e-164 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CS42, Q9CZA9	Gene names	Prps2
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase II (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase II) (PRS-II).

PRPS2_HUMAN
NC score	0.999176 (rank : 5)	θ value	4.40161e-164 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P11908, Q15245	Gene names	PRPS2
Domain Architecture
Description	Ribose-phosphate pyrophosphokinase II (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) (PPRibP).

KPRB_HUMAN
NC score	0.959385 (rank : 6)	θ value	3.82246e-75 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O60256	Gene names	PRPSAP2
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPP synthetase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41).

KPRB_MOUSE
NC score	0.958502 (rank : 7)	θ value	4.22625e-74 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R574	Gene names	Prpsap2
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPP synthetase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41).

KPRA_HUMAN
NC score	0.956061 (rank : 8)	θ value	3.70236e-70 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q14558, Q96H06	Gene names	PRPSAP1
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPP synthetase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP39).

KPRA_MOUSE
NC score	0.955917 (rank : 9)	θ value	6.31527e-70 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0M1	Gene names	Prpsap1
Domain Architecture	No domain graphic available
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPP synthetase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP39).

ZEP1_HUMAN
NC score	0.008967 (rank : 10)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1036	Shared Neighborhood Hits	5
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).