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Network neighborhood for query Sequence : PRP18_MOUSE

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PRP18_MOUSE
SwissProt Accessions	Q8BM39, Q3UX46, Q8BZ54	Gene names	Prpf18, Prp18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRP18_HUMAN
θ value	0 (rank : 1)	NC score	0.997847 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	52	Shared Neighborhood Hits	45
SwissProt Accessions	Q99633, Q9BUI9	Gene names	PRPF18, HPRP18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18).

PRP18_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM39, Q3UX46, Q8BZ54	Gene names	Prpf18, Prp18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog).

PEPL_HUMAN
θ value	0.00390308 (rank : 3)	NC score	0.077307 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	1141	Shared Neighborhood Hits	30
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

GCC2_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.066166 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	1558	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.066289 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	1559	Shared Neighborhood Hits	30
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CJ118_MOUSE
θ value	0.21417 (rank : 6)	NC score	0.072992 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	1132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

LAMA2_HUMAN
θ value	0.21417 (rank : 7)	NC score	0.040830 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SMC3_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.081337 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	1186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.081490 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	1187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

DYXC1_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.089655 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

GLRX5_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.116269 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SX6, Q3YML0, Q86WY3, Q8IZ54	Gene names	GLRX5, C14orf87
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

DYXC1_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.087314 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

KMHN1_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.063418 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	949	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LIPA1_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.062888 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	1294	Shared Neighborhood Hits	32
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

TRHY_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.058583 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	1385	Shared Neighborhood Hits	30
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

FLIP1_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.067612 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	1405	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SNX23_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.044215 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

IF38_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.079395 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

SWP70_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.062554 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TRIPB_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.058894 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ANR12_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.041823 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	1081	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CCD46_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.053837 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	1430	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CJ118_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.063831 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

FLIP1_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.068294 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	1176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SPC24_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.078230 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	324	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

STK10_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.025838 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	1921	Shared Neighborhood Hits	30
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

UT14A_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.056952 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

LIPA2_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.060131 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	1044	Shared Neighborhood Hits	31
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

PITX2_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.023575 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.023367 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

CALD1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.047344 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

PRP4_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.019388 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.019480 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

IRX3_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.024497 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

KIF3A_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.033429 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	715	Shared Neighborhood Hits	29
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

M4K4_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.016411 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	1589	Shared Neighborhood Hits	24
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.016582 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	1560	Shared Neighborhood Hits	23
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

GLRX5_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.068115 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Y14, Q3YML1, Q9D6E9	Gene names	Glrx5
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

ZRF1_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.045479 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

LIPB1_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.048301 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	727	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

SGCE_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.024660 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O70258	Gene names	Sgce
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

UBE3A_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.012646 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

CPSF2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.021331 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

EST1A_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.020050 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

INPP_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.024606 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P49442, Q8R3L1	Gene names	Inpp1
Domain Architecture
Description	Inositol polyphosphate 1-phosphatase (EC 3.1.3.57) (IPPase) (IPP).

PRP31_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.022257 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWY3, Q8N7F9, Q9H271, Q9Y439	Gene names	PRPF31, PRP31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (hPrp31) (Protein 61K) (Serologically defined breast cancer antigen NY-BR-99).

PRP31_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.022242 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCF0, Q6P7X2, Q8BQ91, Q8C8U4, Q8C8V5, Q8CCG6, Q8CF52, Q8VBW3	Gene names	Prpf31, Prp31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (Protein 61K).

STK10_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.024690 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	2132	Shared Neighborhood Hits	29
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GCC2_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.051890 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	1619	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PEPL_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.050674 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	1105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

Hits sorted by NC score

PRP18_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM39, Q3UX46, Q8BZ54	Gene names	Prpf18, Prp18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog).

PRP18_HUMAN
NC score	0.997847 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	52	Shared Neighborhood Hits	45
SwissProt Accessions	Q99633, Q9BUI9	Gene names	PRPF18, HPRP18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18).

GLRX5_HUMAN
NC score	0.116269 (rank : 3)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SX6, Q3YML0, Q86WY3, Q8IZ54	Gene names	GLRX5, C14orf87
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

DYXC1_HUMAN
NC score	0.089655 (rank : 4)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

DYXC1_MOUSE
NC score	0.087314 (rank : 5)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

SMC3_MOUSE
NC score	0.081490 (rank : 6)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	1187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.081337 (rank : 7)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	1186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

IF38_HUMAN
NC score	0.079395 (rank : 8)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

SPC24_HUMAN
NC score	0.078230 (rank : 9)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	324	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

PEPL_HUMAN
NC score	0.077307 (rank : 10)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	1141	Shared Neighborhood Hits	30
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CJ118_MOUSE
NC score	0.072992 (rank : 11)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	1132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

FLIP1_MOUSE
NC score	0.068294 (rank : 12)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	1176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GLRX5_MOUSE
NC score	0.068115 (rank : 13)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Y14, Q3YML1, Q9D6E9	Gene names	Glrx5
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

FLIP1_HUMAN
NC score	0.067612 (rank : 14)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	1405	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RBP24_HUMAN
NC score	0.066289 (rank : 15)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	1559	Shared Neighborhood Hits	30
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.066166 (rank : 16)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	1558	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CJ118_HUMAN
NC score	0.063831 (rank : 17)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

KMHN1_MOUSE
NC score	0.063418 (rank : 18)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	949	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LIPA1_HUMAN
NC score	0.062888 (rank : 19)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	1294	Shared Neighborhood Hits	32
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

SWP70_HUMAN
NC score	0.062554 (rank : 20)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

LIPA2_HUMAN
NC score	0.060131 (rank : 21)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	1044	Shared Neighborhood Hits	31
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TRIPB_HUMAN
NC score	0.058894 (rank : 22)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TRHY_HUMAN
NC score	0.058583 (rank : 23)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	1385	Shared Neighborhood Hits	30
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

UT14A_MOUSE
NC score	0.056952 (rank : 24)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

CCD46_HUMAN
NC score	0.053837 (rank : 25)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	1430	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GCC2_MOUSE
NC score	0.051890 (rank : 26)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	1619	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PEPL_MOUSE
NC score	0.050674 (rank : 27)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	1105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

LIPB1_MOUSE
NC score	0.048301 (rank : 28)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	727	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

CALD1_HUMAN
NC score	0.047344 (rank : 29)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

ZRF1_MOUSE
NC score	0.045479 (rank : 30)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

SNX23_HUMAN
NC score	0.044215 (rank : 31)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ANR12_HUMAN
NC score	0.041823 (rank : 32)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	1081	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

LAMA2_HUMAN
NC score	0.040830 (rank : 33)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KIF3A_MOUSE
NC score	0.033429 (rank : 34)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	715	Shared Neighborhood Hits	29
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

STK10_HUMAN
NC score	0.025838 (rank : 35)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	1921	Shared Neighborhood Hits	30
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
NC score	0.024690 (rank : 36)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	2132	Shared Neighborhood Hits	29
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SGCE_MOUSE
NC score	0.024660 (rank : 37)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O70258	Gene names	Sgce
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

INPP_MOUSE
NC score	0.024606 (rank : 38)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P49442, Q8R3L1	Gene names	Inpp1
Domain Architecture
Description	Inositol polyphosphate 1-phosphatase (EC 3.1.3.57) (IPPase) (IPP).

IRX3_HUMAN
NC score	0.024497 (rank : 39)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

PITX2_HUMAN
NC score	0.023575 (rank : 40)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
NC score	0.023367 (rank : 41)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

PRP31_HUMAN
NC score	0.022257 (rank : 42)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWY3, Q8N7F9, Q9H271, Q9Y439	Gene names	PRPF31, PRP31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (hPrp31) (Protein 61K) (Serologically defined breast cancer antigen NY-BR-99).

PRP31_MOUSE
NC score	0.022242 (rank : 43)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCF0, Q6P7X2, Q8BQ91, Q8C8U4, Q8C8V5, Q8CCG6, Q8CF52, Q8VBW3	Gene names	Prpf31, Prp31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (Protein 61K).

CPSF2_HUMAN
NC score	0.021331 (rank : 44)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

EST1A_MOUSE
NC score	0.020050 (rank : 45)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

PRP4_MOUSE
NC score	0.019480 (rank : 46)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PRP4_HUMAN
NC score	0.019388 (rank : 47)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

M4K4_MOUSE
NC score	0.016582 (rank : 48)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	1560	Shared Neighborhood Hits	23
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.016411 (rank : 49)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	1589	Shared Neighborhood Hits	24
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

UBE3A_HUMAN
NC score	0.012646 (rank : 50)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).