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Network neighborhood for query Sequence : PPCE_HUMAN

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PPCE_HUMAN
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PPCE_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PPCE_MOUSE
θ value	0 (rank : 2)	NC score	0.999400 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

APEH_MOUSE
θ value	0.00869519 (rank : 3)	NC score	0.177700 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

DPP9_HUMAN
θ value	0.0431538 (rank : 4)	NC score	0.138556 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.136517 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP10_MOUSE
θ value	0.125558 (rank : 6)	NC score	0.090469 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP8_MOUSE
θ value	0.163984 (rank : 7)	NC score	0.129191 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

ACPH_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.145774 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

DPP8_HUMAN
θ value	0.279714 (rank : 9)	NC score	0.126105 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP10_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.071500 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

WDR33_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.008798 (rank : 18)
Query Neighborhood Hits	14	Target Neighborhood Hits	638	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

DESC4_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.004205 (rank : 20)
Query Neighborhood Hits	14	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

KRHB4_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.007458 (rank : 19)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

NEBU_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.014358 (rank : 17)
Query Neighborhood Hits	14	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

DPP4_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.052670 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.053343 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP6_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.057521 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.057791 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

SEPR_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.053737 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

SEPR_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.054193 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

Hits sorted by NC score

PPCE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PPCE_MOUSE
NC score	0.999400 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

APEH_MOUSE
NC score	0.177700 (rank : 3)	θ value	0.00869519 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

ACPH_HUMAN
NC score	0.145774 (rank : 4)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

DPP9_HUMAN
NC score	0.138556 (rank : 5)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
NC score	0.136517 (rank : 6)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP8_MOUSE
NC score	0.129191 (rank : 7)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

DPP8_HUMAN
NC score	0.126105 (rank : 8)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP10_MOUSE
NC score	0.090469 (rank : 9)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP10_HUMAN
NC score	0.071500 (rank : 10)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP6_MOUSE
NC score	0.057791 (rank : 11)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_HUMAN
NC score	0.057521 (rank : 12)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

SEPR_MOUSE
NC score	0.054193 (rank : 13)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	14	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

SEPR_HUMAN
NC score	0.053737 (rank : 14)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

DPP4_MOUSE
NC score	0.053343 (rank : 15)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_HUMAN
NC score	0.052670 (rank : 16)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

NEBU_HUMAN
NC score	0.014358 (rank : 17)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

WDR33_HUMAN
NC score	0.008798 (rank : 18)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	638	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

KRHB4_MOUSE
NC score	0.007458 (rank : 19)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

DESC4_MOUSE
NC score	0.004205 (rank : 20)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].