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Network neighborhood for query Sequence : P3_MOUSE

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P3_MOUSE
SwissProt Accessions	P21129, Q8QZR2	Gene names	Slc10a3, P3
Domain Architecture	No domain graphic available
Description	P3 protein (Solute carrier family 10 member 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P3_HUMAN
θ value	0 (rank : 1)	NC score	0.997570 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P09131	Gene names	SLC10A3, DXS253E, P3
Domain Architecture
Description	P3 protein (Solute carrier family 10 member 3).

P3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21129, Q8QZR2	Gene names	Slc10a3, P3
Domain Architecture	No domain graphic available
Description	P3 protein (Solute carrier family 10 member 3).

NTCP_HUMAN
θ value	1.2049e-28 (rank : 3)	NC score	0.793666 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q14973	Gene names	SLC10A1, NTCP
Domain Architecture
Description	Sodium/bile acid cotransporter (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (Solute carrier family 10 member 1).

NTCP_MOUSE
θ value	3.28125e-26 (rank : 4)	NC score	0.788222 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	O08705, Q52L86	Gene names	Slc10a1, Ntcp
Domain Architecture
Description	Sodium/bile acid cotransporter (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (Solute carrier family 10 member 1).

NTCP2_MOUSE
θ value	1.42661e-21 (rank : 5)	NC score	0.749074 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P70172, Q8VI83, Q925U7	Gene names	Slc10a2, Ntcp2
Domain Architecture
Description	Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile acid cotransporter) (Na(+)-dependent ileal bile acid transporter) (Ileal sodium-dependent bile acid transporter) (ISBT) (IBAT) (Apical sodium- dependent bile acid transporter) (ASBT) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2).

NTCP2_HUMAN
θ value	3.28887e-18 (rank : 6)	NC score	0.737797 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q12908, Q13839	Gene names	SLC10A2, NTCP2
Domain Architecture
Description	Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile acid cotransporter) (Na(+)-dependent ileal bile acid transporter) (Ileal sodium-dependent bile acid transporter) (ISBT) (IBAT) (Apical sodium- dependent bile acid transporter) (ASBT) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2).

G137B_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.137897 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

CLD2_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.020583 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P57739	Gene names	CLDN2
Domain Architecture
Description	Claudin-2 (SP82).

CLD2_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.018919 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	O88552	Gene names	Cldn2
Domain Architecture
Description	Claudin-2.

CCRK_HUMAN
θ value	8.99809 (rank : 10)	NC score	-0.000144 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	835	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).

Hits sorted by NC score

P3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21129, Q8QZR2	Gene names	Slc10a3, P3
Domain Architecture	No domain graphic available
Description	P3 protein (Solute carrier family 10 member 3).

P3_HUMAN
NC score	0.997570 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P09131	Gene names	SLC10A3, DXS253E, P3
Domain Architecture
Description	P3 protein (Solute carrier family 10 member 3).

NTCP_HUMAN
NC score	0.793666 (rank : 3)	θ value	1.2049e-28 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q14973	Gene names	SLC10A1, NTCP
Domain Architecture
Description	Sodium/bile acid cotransporter (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (Solute carrier family 10 member 1).

NTCP_MOUSE
NC score	0.788222 (rank : 4)	θ value	3.28125e-26 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	O08705, Q52L86	Gene names	Slc10a1, Ntcp
Domain Architecture
Description	Sodium/bile acid cotransporter (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (Solute carrier family 10 member 1).

NTCP2_MOUSE
NC score	0.749074 (rank : 5)	θ value	1.42661e-21 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P70172, Q8VI83, Q925U7	Gene names	Slc10a2, Ntcp2
Domain Architecture
Description	Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile acid cotransporter) (Na(+)-dependent ileal bile acid transporter) (Ileal sodium-dependent bile acid transporter) (ISBT) (IBAT) (Apical sodium- dependent bile acid transporter) (ASBT) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2).

NTCP2_HUMAN
NC score	0.737797 (rank : 6)	θ value	3.28887e-18 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q12908, Q13839	Gene names	SLC10A2, NTCP2
Domain Architecture
Description	Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile acid cotransporter) (Na(+)-dependent ileal bile acid transporter) (Ileal sodium-dependent bile acid transporter) (ISBT) (IBAT) (Apical sodium- dependent bile acid transporter) (ASBT) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2).

G137B_HUMAN
NC score	0.137897 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

CLD2_HUMAN
NC score	0.020583 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P57739	Gene names	CLDN2
Domain Architecture
Description	Claudin-2 (SP82).

CLD2_MOUSE
NC score	0.018919 (rank : 9)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	O88552	Gene names	Cldn2
Domain Architecture
Description	Claudin-2.

CCRK_HUMAN
NC score	-0.000144 (rank : 10)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	835	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).