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Network neighborhood for query Sequence : OTUB1_HUMAN

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OTUB1_HUMAN
SwissProt Accessions	Q96FW1, Q32Q78, Q96II3, Q9NXQ4, Q9P0B8	Gene names	OTUB1, OTB1, OTU1
Domain Architecture
Description	Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) (Otubain-1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Ubiquitin- specific-processing protease OTUB1) (Deubiquitinating enzyme OTUB1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OTUB1_HUMAN
θ value	1.28662e-147 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q96FW1, Q32Q78, Q96II3, Q9NXQ4, Q9P0B8	Gene names	OTUB1, OTB1, OTU1
Domain Architecture
Description	Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) (Otubain-1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Ubiquitin- specific-processing protease OTUB1) (Deubiquitinating enzyme OTUB1).

OTUB1_MOUSE
θ value	1.68038e-147 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQI3, Q3ULV9, Q3V408, Q8C326, Q8R5F2	Gene names	Otub1
Domain Architecture
Description	Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) (Otubain-1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Ubiquitin- specific-processing protease OTUB1) (Deubiquitinating enzyme OTUB1).

OTUB2_HUMAN
θ value	9.45883e-58 (rank : 3)	NC score	0.948015 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DC9, Q9H6T1	Gene names	OTUB2, C14orf137, OTB2, OTU2
Domain Architecture	No domain graphic available
Description	Ubiquitin thioesterase protein OTUB2 (EC 3.4.-.-) (Otubain-2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Ubiquitin- specific-processing protease OTUB2) (Deubiquitinating enzyme OTUB2).

OTUB2_MOUSE
θ value	1.23536e-57 (rank : 4)	NC score	0.947990 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQX0, Q3TUZ2, Q9D4K8	Gene names	Otub2
Domain Architecture	No domain graphic available
Description	Ubiquitin thioesterase protein OTUB2 (EC 3.4.-.-) (Otubain-2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Ubiquitin- specific-processing protease OTUB2) (Deubiquitinating enzyme OTUB2).

TXLNB_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.025130 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	912	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

KTN1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.015738 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	1197	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LAMA4_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.013741 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	708	Shared Neighborhood Hits	9
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

EVPL_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.011110 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	895	Shared Neighborhood Hits	8
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

HMMR_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.011196 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	1082	Shared Neighborhood Hits	9
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYO5C_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.008011 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	1206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYH9_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.005492 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	1829	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

Hits sorted by NC score

OTUB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.28662e-147 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q96FW1, Q32Q78, Q96II3, Q9NXQ4, Q9P0B8	Gene names	OTUB1, OTB1, OTU1
Domain Architecture
Description	Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) (Otubain-1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Ubiquitin- specific-processing protease OTUB1) (Deubiquitinating enzyme OTUB1).

OTUB1_MOUSE
NC score	0.999962 (rank : 2)	θ value	1.68038e-147 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQI3, Q3ULV9, Q3V408, Q8C326, Q8R5F2	Gene names	Otub1
Domain Architecture
Description	Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) (Otubain-1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Ubiquitin- specific-processing protease OTUB1) (Deubiquitinating enzyme OTUB1).

OTUB2_HUMAN
NC score	0.948015 (rank : 3)	θ value	9.45883e-58 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DC9, Q9H6T1	Gene names	OTUB2, C14orf137, OTB2, OTU2
Domain Architecture	No domain graphic available
Description	Ubiquitin thioesterase protein OTUB2 (EC 3.4.-.-) (Otubain-2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Ubiquitin- specific-processing protease OTUB2) (Deubiquitinating enzyme OTUB2).

OTUB2_MOUSE
NC score	0.947990 (rank : 4)	θ value	1.23536e-57 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQX0, Q3TUZ2, Q9D4K8	Gene names	Otub2
Domain Architecture	No domain graphic available
Description	Ubiquitin thioesterase protein OTUB2 (EC 3.4.-.-) (Otubain-2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Ubiquitin- specific-processing protease OTUB2) (Deubiquitinating enzyme OTUB2).

TXLNB_HUMAN
NC score	0.025130 (rank : 5)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	912	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

KTN1_HUMAN
NC score	0.015738 (rank : 6)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	1197	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LAMA4_HUMAN
NC score	0.013741 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	708	Shared Neighborhood Hits	9
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

HMMR_HUMAN
NC score	0.011196 (rank : 8)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	1082	Shared Neighborhood Hits	9
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

EVPL_HUMAN
NC score	0.011110 (rank : 9)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	895	Shared Neighborhood Hits	8
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MYO5C_HUMAN
NC score	0.008011 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	1206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYH9_MOUSE
NC score	0.005492 (rank : 11)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	1829	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).