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Network neighborhood for query Sequence : NLTP_HUMAN

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NLTP_HUMAN
SwissProt Accessions	P22307, Q15432, Q16622, Q99430	Gene names	SCP2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NLTP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P22307, Q15432, Q16622, Q99430	Gene names	SCP2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

NLTP_MOUSE
θ value	0 (rank : 2)	NC score	0.997632 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P32020, Q9DBM7	Gene names	Scp2, Scp-2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

DHB4_HUMAN
θ value	1.63225e-17 (rank : 3)	NC score	0.422449 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	P51659	Gene names	HSD17B4, EDH17B4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

DHB4_MOUSE
θ value	3.63628e-17 (rank : 4)	NC score	0.421707 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P51660, Q9DBM3	Gene names	Hsd17b4, Edh17b4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

CT079_HUMAN
θ value	2.20605e-14 (rank : 5)	NC score	0.620381 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJQ7	Gene names	C20orf79
Domain Architecture
Description	Uncharacterized protein C20orf79.

THIM_MOUSE
θ value	4.91457e-14 (rank : 6)	NC score	0.538248 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWT1, Q8JZR8	Gene names	Acaa2
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase).

CT079_MOUSE
θ value	1.09485e-13 (rank : 7)	NC score	0.615529 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAH1	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf79 homolog.

THIKB_MOUSE
θ value	1.9326e-10 (rank : 8)	NC score	0.514713 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCH0	Gene names	Acaa1b, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase B, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase B) (Acetyl-CoA acyltransferase B) (Peroxisomal 3-oxoacyl- CoA thiolase B).

THIM_HUMAN
θ value	2.52405e-10 (rank : 9)	NC score	0.520206 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P42765, Q9BUT6	Gene names	ACAA2
Domain Architecture
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase) (T1).

THIKA_MOUSE
θ value	3.29651e-10 (rank : 10)	NC score	0.514297 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q921H8	Gene names	Acaa1a, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase A, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase A) (Acetyl-CoA acyltransferase A) (Peroxisomal 3-oxoacyl- CoA thiolase A).

THIK_HUMAN
θ value	5.62301e-10 (rank : 11)	NC score	0.516814 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	P09110	Gene names	ACAA1, ACAA, PTHIO
Domain Architecture
Description	3-ketoacyl-CoA thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase).

THIC_HUMAN
θ value	1.06045e-08 (rank : 12)	NC score	0.486858 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWD1, Q16146, Q5TCL7, Q8TDM4	Gene names	ACAT2, ACTL
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase) (Acetyl CoA transferase-like protein).

THIC_MOUSE
θ value	1.99992e-07 (rank : 13)	NC score	0.481579 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CAY6, Q3TJY7, Q62292, Q96EB7, Q99K88, Q9CYV2	Gene names	Acat2
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase).

ECHB_HUMAN
θ value	4.45536e-07 (rank : 14)	NC score	0.483603 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P55084, O14969, Q53TA6, Q96C77, Q9H3F5	Gene names	HADHB
Domain Architecture
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

ECHB_MOUSE
θ value	4.45536e-07 (rank : 15)	NC score	0.482748 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JY0, Q3TEH9, Q8BJI5, Q8BJM0, Q8BK52	Gene names	Hadhb
Domain Architecture	No domain graphic available
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

STML1_HUMAN
θ value	5.81887e-07 (rank : 16)	NC score	0.299808 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

STML1_MOUSE
θ value	2.21117e-06 (rank : 17)	NC score	0.291915 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

THIL_MOUSE
θ value	2.44474e-05 (rank : 18)	NC score	0.467733 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8QZT1, Q3TE92	Gene names	Acat1
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, mitochondrial precursor (EC 2.3.1.9) (Acetoacetyl-CoA thiolase).

THIL_HUMAN
θ value	5.44631e-05 (rank : 19)	NC score	0.462462 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P24752	Gene names	ACAT1, ACAT, MAT
Domain Architecture
Description	Acetyl-CoA acetyltransferase, mitochondrial precursor (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2).

THYG_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.027102 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

H2AY_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.023321 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.023331 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

BDH2_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.053165 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZV9	Gene names	Bdh2, Dhrs6
Domain Architecture	No domain graphic available
Description	3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.30) (R-beta- hydroxybutyrate dehydrogenase) (Dehydrogenase/reductase SDR family member 6).

DHB8_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.060804 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q92506, Q9UIQ1	Gene names	HSD17B8, FABGL, HKE6, RING2
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-HSD 8) (17- beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6).

DHB8_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.060993 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P50171, Q60958, Q60959, Q9Z1W2	Gene names	Hsd17b8, H2-Ke6, Hke6
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-HSD 8) (17- beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6).

FVT1_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.050044 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q06136	Gene names	FVT1
Domain Architecture
Description	3-ketodihydrosphingosine reductase precursor (EC 1.1.1.102) (3- dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1).

FVT1_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.050081 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GV12	Gene names	Fvt1
Domain Architecture	No domain graphic available
Description	3-ketodihydrosphingosine reductase precursor (EC 1.1.1.102) (3- dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1).

Hits sorted by NC score

NLTP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P22307, Q15432, Q16622, Q99430	Gene names	SCP2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

NLTP_MOUSE
NC score	0.997632 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P32020, Q9DBM7	Gene names	Scp2, Scp-2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

CT079_HUMAN
NC score	0.620381 (rank : 3)	θ value	2.20605e-14 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJQ7	Gene names	C20orf79
Domain Architecture
Description	Uncharacterized protein C20orf79.

CT079_MOUSE
NC score	0.615529 (rank : 4)	θ value	1.09485e-13 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAH1	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf79 homolog.

THIM_MOUSE
NC score	0.538248 (rank : 5)	θ value	4.91457e-14 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWT1, Q8JZR8	Gene names	Acaa2
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase).

THIM_HUMAN
NC score	0.520206 (rank : 6)	θ value	2.52405e-10 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P42765, Q9BUT6	Gene names	ACAA2
Domain Architecture
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase) (T1).

THIK_HUMAN
NC score	0.516814 (rank : 7)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	P09110	Gene names	ACAA1, ACAA, PTHIO
Domain Architecture
Description	3-ketoacyl-CoA thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase).

THIKB_MOUSE
NC score	0.514713 (rank : 8)	θ value	1.9326e-10 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCH0	Gene names	Acaa1b, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase B, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase B) (Acetyl-CoA acyltransferase B) (Peroxisomal 3-oxoacyl- CoA thiolase B).

THIKA_MOUSE
NC score	0.514297 (rank : 9)	θ value	3.29651e-10 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q921H8	Gene names	Acaa1a, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase A, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase A) (Acetyl-CoA acyltransferase A) (Peroxisomal 3-oxoacyl- CoA thiolase A).

THIC_HUMAN
NC score	0.486858 (rank : 10)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWD1, Q16146, Q5TCL7, Q8TDM4	Gene names	ACAT2, ACTL
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase) (Acetyl CoA transferase-like protein).

ECHB_HUMAN
NC score	0.483603 (rank : 11)	θ value	4.45536e-07 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P55084, O14969, Q53TA6, Q96C77, Q9H3F5	Gene names	HADHB
Domain Architecture
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

ECHB_MOUSE
NC score	0.482748 (rank : 12)	θ value	4.45536e-07 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JY0, Q3TEH9, Q8BJI5, Q8BJM0, Q8BK52	Gene names	Hadhb
Domain Architecture	No domain graphic available
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

THIC_MOUSE
NC score	0.481579 (rank : 13)	θ value	1.99992e-07 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CAY6, Q3TJY7, Q62292, Q96EB7, Q99K88, Q9CYV2	Gene names	Acat2
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase).

THIL_MOUSE
NC score	0.467733 (rank : 14)	θ value	2.44474e-05 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8QZT1, Q3TE92	Gene names	Acat1
Domain Architecture	No domain graphic available
Description	Acetyl-CoA acetyltransferase, mitochondrial precursor (EC 2.3.1.9) (Acetoacetyl-CoA thiolase).

THIL_HUMAN
NC score	0.462462 (rank : 15)	θ value	5.44631e-05 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P24752	Gene names	ACAT1, ACAT, MAT
Domain Architecture
Description	Acetyl-CoA acetyltransferase, mitochondrial precursor (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2).

DHB4_HUMAN
NC score	0.422449 (rank : 16)	θ value	1.63225e-17 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	P51659	Gene names	HSD17B4, EDH17B4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

DHB4_MOUSE
NC score	0.421707 (rank : 17)	θ value	3.63628e-17 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P51660, Q9DBM3	Gene names	Hsd17b4, Edh17b4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

STML1_HUMAN
NC score	0.299808 (rank : 18)	θ value	5.81887e-07 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

STML1_MOUSE
NC score	0.291915 (rank : 19)	θ value	2.21117e-06 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

DHB8_MOUSE
NC score	0.060993 (rank : 20)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P50171, Q60958, Q60959, Q9Z1W2	Gene names	Hsd17b8, H2-Ke6, Hke6
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-HSD 8) (17- beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6).

DHB8_HUMAN
NC score	0.060804 (rank : 21)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q92506, Q9UIQ1	Gene names	HSD17B8, FABGL, HKE6, RING2
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-HSD 8) (17- beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6).

BDH2_MOUSE
NC score	0.053165 (rank : 22)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZV9	Gene names	Bdh2, Dhrs6
Domain Architecture	No domain graphic available
Description	3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.30) (R-beta- hydroxybutyrate dehydrogenase) (Dehydrogenase/reductase SDR family member 6).

FVT1_MOUSE
NC score	0.050081 (rank : 23)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GV12	Gene names	Fvt1
Domain Architecture	No domain graphic available
Description	3-ketodihydrosphingosine reductase precursor (EC 1.1.1.102) (3- dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1).

FVT1_HUMAN
NC score	0.050044 (rank : 24)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q06136	Gene names	FVT1
Domain Architecture
Description	3-ketodihydrosphingosine reductase precursor (EC 1.1.1.102) (3- dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1).

THYG_MOUSE
NC score	0.027102 (rank : 25)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

H2AY_MOUSE
NC score	0.023331 (rank : 26)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AY_HUMAN
NC score	0.023321 (rank : 27)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).