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Network neighborhood for query Sequence : MTHR_MOUSE

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MTHR_MOUSE
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MTHR_HUMAN
θ value	0 (rank : 1)	NC score	0.998531 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

CCAR1_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.034920 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

RB6I2_HUMAN
θ value	2.36792 (rank : 4)	NC score	0.010843 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	1584	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	2.36792 (rank : 5)	NC score	0.011433 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	1433	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

2ACC_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.040357 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

T240L_HUMAN
θ value	8.99809 (rank : 7)	NC score	0.017746 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
θ value	8.99809 (rank : 8)	NC score	0.017718 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

Hits sorted by NC score

MTHR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_HUMAN
NC score	0.998531 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

2ACC_HUMAN
NC score	0.040357 (rank : 3)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

CCAR1_HUMAN
NC score	0.034920 (rank : 4)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

T240L_HUMAN
NC score	0.017746 (rank : 5)	θ value	8.99809 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
NC score	0.017718 (rank : 6)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

RB6I2_MOUSE
NC score	0.011433 (rank : 7)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	1433	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.010843 (rank : 8)	θ value	2.36792 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	1584	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).