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Network neighborhood for query Sequence : MCH_HUMAN

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MCH_HUMAN
SwissProt Accessions	P20382, Q16044	Gene names	PMCH, MCH
Domain Architecture
Description	Pro-MCH precursor [Contains: Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCH_HUMAN
θ value	6.48998e-91 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P20382, Q16044	Gene names	PMCH, MCH
Domain Architecture
Description	Pro-MCH precursor [Contains: Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)].

MCH_MOUSE
θ value	1.26953e-78 (rank : 2)	NC score	0.998116 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P56942	Gene names	Pmch, Mch
Domain Architecture	No domain graphic available
Description	Pro-MCH precursor [Contains: Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)].

MCHL2_HUMAN
θ value	2.96089e-35 (rank : 3)	NC score	0.969533 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQD1	Gene names	PMCHL2
Domain Architecture	No domain graphic available
Description	Pro-MCH-like protein 2 (Pro-melanin-concentrating hormone-like protein 2).

MCHL1_HUMAN
θ value	1.12514e-34 (rank : 4)	NC score	0.968356 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q16048, Q9BQ10	Gene names	PMCHL1
Domain Architecture	No domain graphic available
Description	Pro-MCH-like protein 1 (Pro-melanin-concentrating hormone-like protein 1) (Pro-MCH variant).

WNK3_HUMAN
θ value	5.27518 (rank : 5)	NC score	0.004043 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	948	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

M3K4_HUMAN
θ value	8.99809 (rank : 6)	NC score	0.001734 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

Hits sorted by NC score

MCH_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.48998e-91 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P20382, Q16044	Gene names	PMCH, MCH
Domain Architecture
Description	Pro-MCH precursor [Contains: Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)].

MCH_MOUSE
NC score	0.998116 (rank : 2)	θ value	1.26953e-78 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P56942	Gene names	Pmch, Mch
Domain Architecture	No domain graphic available
Description	Pro-MCH precursor [Contains: Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)].

MCHL2_HUMAN
NC score	0.969533 (rank : 3)	θ value	2.96089e-35 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQD1	Gene names	PMCHL2
Domain Architecture	No domain graphic available
Description	Pro-MCH-like protein 2 (Pro-melanin-concentrating hormone-like protein 2).

MCHL1_HUMAN
NC score	0.968356 (rank : 4)	θ value	1.12514e-34 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q16048, Q9BQ10	Gene names	PMCHL1
Domain Architecture	No domain graphic available
Description	Pro-MCH-like protein 1 (Pro-melanin-concentrating hormone-like protein 1) (Pro-MCH variant).

WNK3_HUMAN
NC score	0.004043 (rank : 5)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	948	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

M3K4_HUMAN
NC score	0.001734 (rank : 6)	θ value	8.99809 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).