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Network neighborhood for query Sequence : LCB1_HUMAN

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LCB1_HUMAN
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LCB1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999053 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB2_HUMAN
θ value	5.76516e-39 (rank : 3)	NC score	0.851145 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_MOUSE
θ value	7.52953e-39 (rank : 4)	NC score	0.850848 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

KBL_MOUSE
θ value	3.61944e-33 (rank : 5)	NC score	0.850237 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
θ value	3.17079e-29 (rank : 6)	NC score	0.842370 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

HEM0_MOUSE
θ value	3.50572e-28 (rank : 7)	NC score	0.796817 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM0_HUMAN
θ value	5.97985e-28 (rank : 8)	NC score	0.795048 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM1_HUMAN
θ value	4.01107e-24 (rank : 9)	NC score	0.778856 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_MOUSE
θ value	8.93572e-24 (rank : 10)	NC score	0.772738 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

K1279_MOUSE
θ value	0.47712 (rank : 11)	NC score	0.073746 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPU9, Q5BKR5, Q7TPE0, Q80VQ5, Q8BZE2, Q8CFS7	Gene names	Kiaa1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

K1279_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.066669 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EK5, Q9BR89, Q9ULE1, Q9Y428	Gene names	KIAA1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

SLIT1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.006680 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	715	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CKAP4_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.011564 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	596	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

FYCO1_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.006864 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1059	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

PININ_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.009023 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	753	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CCG7_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.024289 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P62955, Q8VBX3, Q8WXS6, Q9BXT1	Gene names	CACNG7
Domain Architecture	No domain graphic available
Description	Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit).

CCG7_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.024289 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P62956, Q8VBX3, Q8WXS6, Q9BXT1	Gene names	Cacng7
Domain Architecture	No domain graphic available
Description	Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit).

SLIT1_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.005612 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

MPP2_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.005419 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

UGGG2_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.009223 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

CT038_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.192935 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

Hits sorted by NC score

LCB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB1_MOUSE
NC score	0.999053 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB2_HUMAN
NC score	0.851145 (rank : 3)	θ value	5.76516e-39 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_MOUSE
NC score	0.850848 (rank : 4)	θ value	7.52953e-39 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

KBL_MOUSE
NC score	0.850237 (rank : 5)	θ value	3.61944e-33 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
NC score	0.842370 (rank : 6)	θ value	3.17079e-29 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

HEM0_MOUSE
NC score	0.796817 (rank : 7)	θ value	3.50572e-28 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM0_HUMAN
NC score	0.795048 (rank : 8)	θ value	5.97985e-28 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM1_HUMAN
NC score	0.778856 (rank : 9)	θ value	4.01107e-24 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_MOUSE
NC score	0.772738 (rank : 10)	θ value	8.93572e-24 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

CT038_HUMAN
NC score	0.192935 (rank : 11)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

K1279_MOUSE
NC score	0.073746 (rank : 12)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPU9, Q5BKR5, Q7TPE0, Q80VQ5, Q8BZE2, Q8CFS7	Gene names	Kiaa1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

K1279_HUMAN
NC score	0.066669 (rank : 13)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EK5, Q9BR89, Q9ULE1, Q9Y428	Gene names	KIAA1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

CCG7_HUMAN
NC score	0.024289 (rank : 14)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P62955, Q8VBX3, Q8WXS6, Q9BXT1	Gene names	CACNG7
Domain Architecture	No domain graphic available
Description	Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit).

CCG7_MOUSE
NC score	0.024289 (rank : 15)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P62956, Q8VBX3, Q8WXS6, Q9BXT1	Gene names	Cacng7
Domain Architecture	No domain graphic available
Description	Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit).

CKAP4_MOUSE
NC score	0.011564 (rank : 16)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	596	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

UGGG2_HUMAN
NC score	0.009223 (rank : 17)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

PININ_HUMAN
NC score	0.009023 (rank : 18)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	753	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

FYCO1_MOUSE
NC score	0.006864 (rank : 19)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1059	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

SLIT1_MOUSE
NC score	0.006680 (rank : 20)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	715	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.005612 (rank : 21)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

MPP2_MOUSE
NC score	0.005419 (rank : 22)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).