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Network neighborhood for query Sequence : IPP2_HUMAN

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IPP2_HUMAN
SwissProt Accessions	P41236	Gene names	PPP1R2, IPP2
Domain Architecture
Description	Protein phosphatase inhibitor 2 (IPP-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IPP2_HUMAN
θ value	2.30293e-96 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P41236	Gene names	PPP1R2, IPP2
Domain Architecture
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP2_MOUSE
θ value	4.66183e-81 (rank : 2)	NC score	0.972891 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP4_HUMAN
θ value	3.3877e-31 (rank : 3)	NC score	0.883199 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

NOP14_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.102721 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

BPA1_MOUSE
θ value	1.81305 (rank : 5)	NC score	0.014959 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MRCKB_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.007101 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	2239	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.007508 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	2180	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RAD50_MOUSE
θ value	5.27518 (rank : 8)	NC score	0.012164 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	1366	Shared Neighborhood Hits	7
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ZHX1_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.015319 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	334	Shared Neighborhood Hits	2
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

SPTB1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.011576 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

FRAP_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.019392 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.019638 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

LRRK2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.005206 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	1382	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

LRRK2_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.005314 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1359	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

NOP14_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.056023 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

Hits sorted by NC score

IPP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.30293e-96 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P41236	Gene names	PPP1R2, IPP2
Domain Architecture
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP2_MOUSE
NC score	0.972891 (rank : 2)	θ value	4.66183e-81 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP4_HUMAN
NC score	0.883199 (rank : 3)	θ value	3.3877e-31 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

NOP14_HUMAN
NC score	0.102721 (rank : 4)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NOP14_MOUSE
NC score	0.056023 (rank : 5)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

FRAP_MOUSE
NC score	0.019638 (rank : 6)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.019392 (rank : 7)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

ZHX1_MOUSE
NC score	0.015319 (rank : 8)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	334	Shared Neighborhood Hits	2
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

BPA1_MOUSE
NC score	0.014959 (rank : 9)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RAD50_MOUSE
NC score	0.012164 (rank : 10)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1366	Shared Neighborhood Hits	7
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SPTB1_MOUSE
NC score	0.011576 (rank : 11)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

MRCKB_MOUSE
NC score	0.007508 (rank : 12)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	2180	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_HUMAN
NC score	0.007101 (rank : 13)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	2239	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LRRK2_MOUSE
NC score	0.005314 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1359	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

LRRK2_HUMAN
NC score	0.005206 (rank : 15)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1382	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).