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Network neighborhood for query Sequence : IMDH2_MOUSE

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IMDH2_MOUSE
SwissProt Accessions	P24547, Q61734, Q91Z11	Gene names	Impdh2, Impdh
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 2 (EC 1.1.1.205) (IMP dehydrogenase 2) (IMPDH-II) (IMPD 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMDH1_HUMAN
θ value	0 (rank : 1)	NC score	0.998443 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20839, Q8N194, Q96NU2	Gene names	IMPDH1, IMPD1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

IMDH1_MOUSE
θ value	0 (rank : 2)	NC score	0.998318 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	P50096	Gene names	Impdh1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

IMDH2_HUMAN
θ value	0 (rank : 3)	NC score	0.999624 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	P12268, Q6LEF3	Gene names	IMPDH2, IMPD2
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 2 (EC 1.1.1.205) (IMP dehydrogenase 2) (IMPDH-II) (IMPD 2).

IMDH2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P24547, Q61734, Q91Z11	Gene names	Impdh2, Impdh
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 2 (EC 1.1.1.205) (IMP dehydrogenase 2) (IMPDH-II) (IMPD 2).

GMPR2_HUMAN
θ value	1.85889e-29 (rank : 5)	NC score	0.751824 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2T1, Q6IAJ8	Gene names	GMPR2
Domain Architecture
Description	GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2).

GMPR1_HUMAN
θ value	2.42779e-29 (rank : 6)	NC score	0.752313 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

GMPR2_MOUSE
θ value	9.2256e-29 (rank : 7)	NC score	0.750370 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L27, Q8R1T5	Gene names	Gmpr2
Domain Architecture
Description	GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2).

GMPR1_MOUSE
θ value	1.57365e-28 (rank : 8)	NC score	0.752228 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCZ1	Gene names	Gmpr, Gmpr1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

HAOX1_MOUSE
θ value	0.813845 (rank : 9)	NC score	0.077644 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU19	Gene names	Hao1, Gox1, Hao-1
Domain Architecture
Description	Hydroxyacid oxidase 1 (EC 1.1.3.15) (HAOX1) (Glycolate oxidase) (GOX).

HAOX1_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.067114 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJM8, Q9UPZ0, Q9Y3I7	Gene names	HAO1, GOX1, HAOX1
Domain Architecture
Description	Hydroxyacid oxidase 1 (EC 1.1.3.15) (HAOX1) (Glycolate oxidase) (GOX).

BPAEA_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.004042 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	1369	Shared Neighborhood Hits	3
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

F120A_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.014289 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

HAOX2_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.068910 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ3, Q9UJS6	Gene names	HAO2, HAOX2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long- chain L-2-hydroxy acid oxidase).

TXND2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.008319 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	828	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

HAOX2_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.067662 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ2, Q9JHS7, Q9JI00	Gene names	Hao2, Hao3, Haox2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase).

Hits sorted by NC score

IMDH2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P24547, Q61734, Q91Z11	Gene names	Impdh2, Impdh
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 2 (EC 1.1.1.205) (IMP dehydrogenase 2) (IMPDH-II) (IMPD 2).

IMDH2_HUMAN
NC score	0.999624 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	P12268, Q6LEF3	Gene names	IMPDH2, IMPD2
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 2 (EC 1.1.1.205) (IMP dehydrogenase 2) (IMPDH-II) (IMPD 2).

IMDH1_HUMAN
NC score	0.998443 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20839, Q8N194, Q96NU2	Gene names	IMPDH1, IMPD1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

IMDH1_MOUSE
NC score	0.998318 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	P50096	Gene names	Impdh1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

GMPR1_HUMAN
NC score	0.752313 (rank : 5)	θ value	2.42779e-29 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

GMPR1_MOUSE
NC score	0.752228 (rank : 6)	θ value	1.57365e-28 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCZ1	Gene names	Gmpr, Gmpr1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

GMPR2_HUMAN
NC score	0.751824 (rank : 7)	θ value	1.85889e-29 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2T1, Q6IAJ8	Gene names	GMPR2
Domain Architecture
Description	GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2).

GMPR2_MOUSE
NC score	0.750370 (rank : 8)	θ value	9.2256e-29 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L27, Q8R1T5	Gene names	Gmpr2
Domain Architecture
Description	GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2).

HAOX1_MOUSE
NC score	0.077644 (rank : 9)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU19	Gene names	Hao1, Gox1, Hao-1
Domain Architecture
Description	Hydroxyacid oxidase 1 (EC 1.1.3.15) (HAOX1) (Glycolate oxidase) (GOX).

HAOX2_HUMAN
NC score	0.068910 (rank : 10)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ3, Q9UJS6	Gene names	HAO2, HAOX2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long- chain L-2-hydroxy acid oxidase).

HAOX2_MOUSE
NC score	0.067662 (rank : 11)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ2, Q9JHS7, Q9JI00	Gene names	Hao2, Hao3, Haox2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase).

HAOX1_HUMAN
NC score	0.067114 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJM8, Q9UPZ0, Q9Y3I7	Gene names	HAO1, GOX1, HAOX1
Domain Architecture
Description	Hydroxyacid oxidase 1 (EC 1.1.3.15) (HAOX1) (Glycolate oxidase) (GOX).

F120A_HUMAN
NC score	0.014289 (rank : 13)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

TXND2_MOUSE
NC score	0.008319 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	828	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BPAEA_HUMAN
NC score	0.004042 (rank : 15)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1369	Shared Neighborhood Hits	3
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).