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Network neighborhood for query Sequence : IL2_MOUSE

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IL2_MOUSE
SwissProt Accessions	P04351, P97945	Gene names	Il2, Il-2
Domain Architecture
Description	Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IL2_MOUSE
θ value	1.96772e-63 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P04351, P97945	Gene names	Il2, Il-2
Domain Architecture
Description	Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF).

IL2_HUMAN
θ value	1.24399e-33 (rank : 2)	NC score	0.950991 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	P60568, P01585	Gene names	IL2
Domain Architecture
Description	Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin).

STIM2_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.092590 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

STIM2_MOUSE
θ value	0.813845 (rank : 4)	NC score	0.087726 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

EP15R_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.036211 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.037111 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

MED12_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.059231 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MACF1_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.031737 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1341	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.036065 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1321	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

TEX14_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.017296 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	1333	Shared Neighborhood Hits	6
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

MACF1_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.028786 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	1313	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

K1H1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.006936 (rank : 14)
Query Neighborhood Hits	12	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

STIM1_HUMAN
θ value	θ > 10 (rank : 13)	NC score	0.051048 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	665	Shared Neighborhood Hits	7
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	θ > 10 (rank : 14)	NC score	0.051086 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	660	Shared Neighborhood Hits	7
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

Hits sorted by NC score

IL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.96772e-63 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P04351, P97945	Gene names	Il2, Il-2
Domain Architecture
Description	Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF).

IL2_HUMAN
NC score	0.950991 (rank : 2)	θ value	1.24399e-33 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	P60568, P01585	Gene names	IL2
Domain Architecture
Description	Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin).

STIM2_HUMAN
NC score	0.092590 (rank : 3)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

STIM2_MOUSE
NC score	0.087726 (rank : 4)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

MED12_HUMAN
NC score	0.059231 (rank : 5)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

STIM1_MOUSE
NC score	0.051086 (rank : 6)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	12	Target Neighborhood Hits	660	Shared Neighborhood Hits	7
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_HUMAN
NC score	0.051048 (rank : 7)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	665	Shared Neighborhood Hits	7
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

EP15R_MOUSE
NC score	0.037111 (rank : 8)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15R_HUMAN
NC score	0.036211 (rank : 9)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

MACF4_HUMAN
NC score	0.036065 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	1321	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.031737 (rank : 11)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	1341	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
NC score	0.028786 (rank : 12)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1313	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TEX14_MOUSE
NC score	0.017296 (rank : 13)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1333	Shared Neighborhood Hits	6
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

K1H1_HUMAN
NC score	0.006936 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).