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Network neighborhood for query Sequence : IER5_HUMAN

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IER5_HUMAN
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IER5_HUMAN
θ value	3.31772e-103 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER5_MOUSE
θ value	8.51556e-75 (rank : 2)	NC score	0.930859 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER2_HUMAN
θ value	1.33837e-11 (rank : 3)	NC score	0.632666 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

IER2_MOUSE
θ value	9.59137e-10 (rank : 4)	NC score	0.600058 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

GNAS1_MOUSE
θ value	0.0193708 (rank : 5)	NC score	0.063075 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SF3B1_HUMAN
θ value	0.0330416 (rank : 6)	NC score	0.144821 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0330416 (rank : 7)	NC score	0.144670 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

MUC1_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.060234 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	975	Shared Neighborhood Hits	26
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RGS3_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.046468 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	1621	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CD2_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.055627 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	504	Shared Neighborhood Hits	12
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CEL_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.037022 (rank : 54)
Query Neighborhood Hits	47	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RIMB1_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.045919 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	1479	Shared Neighborhood Hits	24
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

OGFR_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.062498 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MILK1_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.043735 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	788	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TSNA1_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.043415 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

PROP_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.019651 (rank : 62)
Query Neighborhood Hits	47	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

LAD1_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.037152 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MDC1_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.036509 (rank : 55)
Query Neighborhood Hits	47	Target Neighborhood Hits	1446	Shared Neighborhood Hits	24
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NRX2A_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.029674 (rank : 59)
Query Neighborhood Hits	47	Target Neighborhood Hits	614	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.040874 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	481	Shared Neighborhood Hits	11
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

RFIP3_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.024267 (rank : 61)
Query Neighborhood Hits	47	Target Neighborhood Hits	1055	Shared Neighborhood Hits	16
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

ZAR1_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.048212 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

LTBP2_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.010070 (rank : 70)
Query Neighborhood Hits	47	Target Neighborhood Hits	617	Shared Neighborhood Hits	6
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NCOA6_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.033787 (rank : 57)
Query Neighborhood Hits	47	Target Neighborhood Hits	1202	Shared Neighborhood Hits	27
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PSL1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.036436 (rank : 56)
Query Neighborhood Hits	47	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CK024_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.050812 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

FOXN1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.017381 (rank : 65)
Query Neighborhood Hits	47	Target Neighborhood Hits	377	Shared Neighborhood Hits	13
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

NPBL_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.018727 (rank : 63)
Query Neighborhood Hits	47	Target Neighborhood Hits	1041	Shared Neighborhood Hits	11
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PRRT3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.060580 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	998	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SOX13_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.018476 (rank : 64)
Query Neighborhood Hits	47	Target Neighborhood Hits	495	Shared Neighborhood Hits	12
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

ZEP1_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.012145 (rank : 68)
Query Neighborhood Hits	47	Target Neighborhood Hits	1063	Shared Neighborhood Hits	16
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

OBF1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.042582 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

ZN142_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.002980 (rank : 73)
Query Neighborhood Hits	47	Target Neighborhood Hits	1007	Shared Neighborhood Hits	13
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

BAT3_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.056880 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.060386 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	518	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

IL4RA_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.024566 (rank : 60)
Query Neighborhood Hits	47	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

BSN_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.040218 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	2057	Shared Neighborhood Hits	37
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

E2AK1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.006539 (rank : 72)
Query Neighborhood Hits	47	Target Neighborhood Hits	833	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

E2AK1_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.006663 (rank : 71)
Query Neighborhood Hits	47	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

IASPP_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.030399 (rank : 58)
Query Neighborhood Hits	47	Target Neighborhood Hits	1024	Shared Neighborhood Hits	23
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NOTC3_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.010975 (rank : 69)
Query Neighborhood Hits	47	Target Neighborhood Hits	1062	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCLO_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.042942 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	2275	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PHLB1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.013289 (rank : 67)
Query Neighborhood Hits	47	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SNPC4_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.037216 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SPT5H_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.040163 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	436	Shared Neighborhood Hits	20
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.040322 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	437	Shared Neighborhood Hits	19
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

UBP42_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.014792 (rank : 66)
Query Neighborhood Hits	47	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

BASP_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.062470 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.073097 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	260	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN032_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.057127 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	267	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.054222 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

GGN_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.056914 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MARCS_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.066644 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MUC1_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.050593 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC7_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.057858 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	538	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRB3_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.076338 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	318	Shared Neighborhood Hits	28
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.076468 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	330	Shared Neighborhood Hits	25
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.074722 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.075604 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	347	Shared Neighborhood Hits	26
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.054238 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPE_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.050170 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.060866 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	460	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.054990 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.067564 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SF3A2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.054371 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	263	Shared Neighborhood Hits	24
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.052970 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SMR3A_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.058546 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

TAF4_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.061753 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	687	Shared Neighborhood Hits	32
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WASIP_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.054996 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	458	Shared Neighborhood Hits	25
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.053099 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBP11_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.052147 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WIRE_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.057485 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.052449 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	310	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

Hits sorted by NC score

IER5_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.31772e-103 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER5_MOUSE
NC score	0.930859 (rank : 2)	θ value	8.51556e-75 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER2_HUMAN
NC score	0.632666 (rank : 3)	θ value	1.33837e-11 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

IER2_MOUSE
NC score	0.600058 (rank : 4)	θ value	9.59137e-10 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

SF3B1_HUMAN
NC score	0.144821 (rank : 5)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.144670 (rank : 6)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PRB4S_HUMAN
NC score	0.076468 (rank : 7)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	47	Target Neighborhood Hits	330	Shared Neighborhood Hits	25
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRB3_HUMAN
NC score	0.076338 (rank : 8)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	47	Target Neighborhood Hits	318	Shared Neighborhood Hits	28
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRP2_MOUSE
NC score	0.075604 (rank : 9)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	47	Target Neighborhood Hits	347	Shared Neighborhood Hits	26
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP1_HUMAN
NC score	0.074722 (rank : 10)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

BASP_MOUSE
NC score	0.073097 (rank : 11)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	260	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PRR13_MOUSE
NC score	0.067564 (rank : 12)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

MARCS_MOUSE
NC score	0.066644 (rank : 13)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

GNAS1_MOUSE
NC score	0.063075 (rank : 14)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

OGFR_HUMAN
NC score	0.062498 (rank : 15)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BASP_HUMAN
NC score	0.062470 (rank : 16)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TAF4_HUMAN
NC score	0.061753 (rank : 17)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	47	Target Neighborhood Hits	687	Shared Neighborhood Hits	32
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRR12_HUMAN
NC score	0.060866 (rank : 18)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	47	Target Neighborhood Hits	460	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRRT3_HUMAN
NC score	0.060580 (rank : 19)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	998	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BAT3_MOUSE
NC score	0.060386 (rank : 20)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	518	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MUC1_HUMAN
NC score	0.060234 (rank : 21)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	975	Shared Neighborhood Hits	26
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SMR3A_HUMAN
NC score	0.058546 (rank : 22)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

MUC7_HUMAN
NC score	0.057858 (rank : 23)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	47	Target Neighborhood Hits	538	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

WIRE_HUMAN
NC score	0.057485 (rank : 24)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CN032_HUMAN
NC score	0.057127 (rank : 25)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	267	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

GGN_HUMAN
NC score	0.056914 (rank : 26)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

BAT3_HUMAN
NC score	0.056880 (rank : 27)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CD2_HUMAN
NC score	0.055627 (rank : 28)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	504	Shared Neighborhood Hits	12
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

WASIP_HUMAN
NC score	0.054996 (rank : 29)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	47	Target Neighborhood Hits	458	Shared Neighborhood Hits	25
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRR13_HUMAN
NC score	0.054990 (rank : 30)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	47	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SF3A2_HUMAN
NC score	0.054371 (rank : 31)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	47	Target Neighborhood Hits	263	Shared Neighborhood Hits	24
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PRP5_HUMAN
NC score	0.054238 (rank : 32)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	47	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

CN032_MOUSE
NC score	0.054222 (rank : 33)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

WASIP_MOUSE
NC score	0.053099 (rank : 34)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	47	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SF3A2_MOUSE
NC score	0.052970 (rank : 35)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WIRE_MOUSE
NC score	0.052449 (rank : 36)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	47	Target Neighborhood Hits	310	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WBP11_HUMAN
NC score	0.052147 (rank : 37)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	47	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CK024_HUMAN
NC score	0.050812 (rank : 38)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MUC1_MOUSE
NC score	0.050593 (rank : 39)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	47	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PRPE_HUMAN
NC score	0.050170 (rank : 40)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

ZAR1_MOUSE
NC score	0.048212 (rank : 41)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

RGS3_MOUSE
NC score	0.046468 (rank : 42)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	1621	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RIMB1_HUMAN
NC score	0.045919 (rank : 43)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	1479	Shared Neighborhood Hits	24
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MILK1_MOUSE
NC score	0.043735 (rank : 44)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	788	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TSNA1_HUMAN
NC score	0.043415 (rank : 45)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

PCLO_MOUSE
NC score	0.042942 (rank : 46)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	2275	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

OBF1_HUMAN
NC score	0.042582 (rank : 47)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

NRX2B_HUMAN
NC score	0.040874 (rank : 48)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	481	Shared Neighborhood Hits	11
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SPT5H_MOUSE
NC score	0.040322 (rank : 49)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	437	Shared Neighborhood Hits	19
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

BSN_MOUSE
NC score	0.040218 (rank : 50)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	2057	Shared Neighborhood Hits	37
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SPT5H_HUMAN
NC score	0.040163 (rank : 51)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	436	Shared Neighborhood Hits	20
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SNPC4_HUMAN
NC score	0.037216 (rank : 52)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

LAD1_HUMAN
NC score	0.037152 (rank : 53)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

CEL_HUMAN
NC score	0.037022 (rank : 54)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

MDC1_HUMAN
NC score	0.036509 (rank : 55)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	1446	Shared Neighborhood Hits	24
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PSL1_HUMAN
NC score	0.036436 (rank : 56)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

NCOA6_HUMAN
NC score	0.033787 (rank : 57)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	1202	Shared Neighborhood Hits	27
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

IASPP_MOUSE
NC score	0.030399 (rank : 58)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	1024	Shared Neighborhood Hits	23
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NRX2A_HUMAN
NC score	0.029674 (rank : 59)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	614	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

IL4RA_HUMAN
NC score	0.024566 (rank : 60)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

RFIP3_HUMAN
NC score	0.024267 (rank : 61)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	1055	Shared Neighborhood Hits	16
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

PROP_HUMAN
NC score	0.019651 (rank : 62)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

NPBL_MOUSE
NC score	0.018727 (rank : 63)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	1041	Shared Neighborhood Hits	11
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SOX13_MOUSE
NC score	0.018476 (rank : 64)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	495	Shared Neighborhood Hits	12
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

FOXN1_HUMAN
NC score	0.017381 (rank : 65)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	377	Shared Neighborhood Hits	13
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

UBP42_HUMAN
NC score	0.014792 (rank : 66)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

PHLB1_HUMAN
NC score	0.013289 (rank : 67)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ZEP1_MOUSE
NC score	0.012145 (rank : 68)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	1063	Shared Neighborhood Hits	16
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

NOTC3_HUMAN
NC score	0.010975 (rank : 69)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	1062	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LTBP2_MOUSE
NC score	0.010070 (rank : 70)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	617	Shared Neighborhood Hits	6
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

E2AK1_MOUSE
NC score	0.006663 (rank : 71)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

E2AK1_HUMAN
NC score	0.006539 (rank : 72)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	833	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

ZN142_HUMAN
NC score	0.002980 (rank : 73)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	1007	Shared Neighborhood Hits	13
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).