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Network neighborhood for query Sequence : ICT1_MOUSE

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ICT1_MOUSE
SwissProt Accessions	Q8R035, Q9CTK1, Q9D1R3	Gene names	Ict1
Domain Architecture	No domain graphic available
Description	Immature colon carcinoma transcript 1 protein precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ICT1_MOUSE
θ value	2.54029e-103 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R035, Q9CTK1, Q9D1R3	Gene names	Ict1
Domain Architecture	No domain graphic available
Description	Immature colon carcinoma transcript 1 protein precursor.

ICT1_HUMAN
θ value	4.50487e-84 (rank : 2)	NC score	0.988803 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q14197, Q53HM7, Q53Y11	Gene names	ICT1, DS1
Domain Architecture
Description	Immature colon carcinoma transcript 1 protein precursor (Digestion substraction 1) (DS-1).

RPC5_MOUSE
θ value	0.813845 (rank : 3)	NC score	0.097326 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

PEPL_MOUSE
θ value	1.38821 (rank : 4)	NC score	0.025271 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	1105	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

NIN_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.023503 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	1416	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PLEC1_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.016654 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	1326	Shared Neighborhood Hits	8
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

M4K4_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.008140 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	1589	Shared Neighborhood Hits	9
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.008491 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1560	Shared Neighborhood Hits	9
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CE290_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.014516 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1553	Shared Neighborhood Hits	10
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

NIN_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.022395 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	1376	Shared Neighborhood Hits	9
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TAF3_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.017451 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CD2L1_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.003837 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	1463	Shared Neighborhood Hits	8
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

RPC5_HUMAN
θ value	θ > 10 (rank : 13)	NC score	0.068021 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

Hits sorted by NC score

ICT1_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.54029e-103 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R035, Q9CTK1, Q9D1R3	Gene names	Ict1
Domain Architecture	No domain graphic available
Description	Immature colon carcinoma transcript 1 protein precursor.

ICT1_HUMAN
NC score	0.988803 (rank : 2)	θ value	4.50487e-84 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q14197, Q53HM7, Q53Y11	Gene names	ICT1, DS1
Domain Architecture
Description	Immature colon carcinoma transcript 1 protein precursor (Digestion substraction 1) (DS-1).

RPC5_MOUSE
NC score	0.097326 (rank : 3)	θ value	0.813845 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

RPC5_HUMAN
NC score	0.068021 (rank : 4)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

PEPL_MOUSE
NC score	0.025271 (rank : 5)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	1105	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

NIN_HUMAN
NC score	0.023503 (rank : 6)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	1416	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
NC score	0.022395 (rank : 7)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1376	Shared Neighborhood Hits	9
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TAF3_MOUSE
NC score	0.017451 (rank : 8)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PLEC1_HUMAN
NC score	0.016654 (rank : 9)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	1326	Shared Neighborhood Hits	8
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CE290_HUMAN
NC score	0.014516 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	1553	Shared Neighborhood Hits	10
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

M4K4_MOUSE
NC score	0.008491 (rank : 11)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	1560	Shared Neighborhood Hits	9
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.008140 (rank : 12)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	1589	Shared Neighborhood Hits	9
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CD2L1_MOUSE
NC score	0.003837 (rank : 13)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	1463	Shared Neighborhood Hits	8
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).