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Network neighborhood for query Sequence : I10R2_HUMAN

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I10R2_HUMAN
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

I10R2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

I10R2_MOUSE
θ value	1.24909e-134 (rank : 2)	NC score	0.968049 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

INAR1_HUMAN
θ value	2.27762e-19 (rank : 3)	NC score	0.680894 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

I20RA_HUMAN
θ value	4.29542e-18 (rank : 4)	NC score	0.676216 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

INGR2_HUMAN
θ value	2.13179e-17 (rank : 5)	NC score	0.675115 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	P38484, Q9BTL5	Gene names	IFNGR2, IFNGT1
Domain Architecture
Description	Interferon-gamma receptor beta chain precursor (Interferon-gamma receptor accessory factor 1) (AF-1) (Interferon-gamma transducer 1).

INAR1_MOUSE
θ value	1.058e-16 (rank : 6)	NC score	0.657805 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

I20RA_MOUSE
θ value	1.29331e-14 (rank : 7)	NC score	0.632123 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

I20RB_HUMAN
θ value	7.84624e-12 (rank : 8)	NC score	0.645454 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UXL0, Q6P438, Q8TAJ7	Gene names	IL20RB, DIRS1
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor beta chain precursor (IL-20R-beta) (IL-20R2).

I22RA_MOUSE
θ value	2.61198e-07 (rank : 9)	NC score	0.563547 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XF5, Q7TNI5	Gene names	Il22ra2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

TF_MOUSE
θ value	5.81887e-07 (rank : 10)	NC score	0.301339 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P20352	Gene names	F3, Cf-3, Cf3
Domain Architecture
Description	Tissue factor precursor (TF) (Coagulation factor III) (CD142 antigen).

INGR1_HUMAN
θ value	1.43324e-05 (rank : 11)	NC score	0.403977 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P15260	Gene names	IFNGR1
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen) (CDw119).

I22RA_HUMAN
θ value	3.19293e-05 (rank : 12)	NC score	0.510407 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q969J5, Q6UWM1, Q96A41, Q96QR0	Gene names	IL22RA2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family class II member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

IL3RB_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.203130 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

INGR1_MOUSE
θ value	0.000602161 (rank : 14)	NC score	0.339669 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

I10R1_HUMAN
θ value	0.00134147 (rank : 15)	NC score	0.272390 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q13651	Gene names	IL10RA, IL10R
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

IL3B2_MOUSE
θ value	0.00228821 (rank : 16)	NC score	0.164091 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	372	Shared Neighborhood Hits	16
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	0.00390308 (rank : 17)	NC score	0.181099 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

TF_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.349282 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P13726, Q6FHG2	Gene names	F3
Domain Architecture
Description	Tissue factor precursor (TF) (Coagulation factor III) (Thromboplastin) (CD142 antigen).

I28RA_HUMAN
θ value	0.0431538 (rank : 19)	NC score	0.292622 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

I10R1_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.285417 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q61727	Gene names	Il10ra, Il10r
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

IL21R_MOUSE
θ value	0.0736092 (rank : 21)	NC score	0.103701 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL27B_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.116486 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

I28RA_MOUSE
θ value	0.21417 (rank : 23)	NC score	0.259128 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGK5, Q6PEV1	Gene names	Il28ra, Ifnlr1
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1).

SUSD3_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.063140 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

INSR_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.013784 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	968	Shared Neighborhood Hits	9
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EPHA2_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.019142 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	1021	Shared Neighborhood Hits	20
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.016358 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	1020	Shared Neighborhood Hits	18
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

IL5RA_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.074399 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

CNTN3_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.016913 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

LEPR_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.052201 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

IL21R_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.086618 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

USH2A_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.018835 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	626	Shared Neighborhood Hits	14
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

I27RA_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.026080 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

SDK2_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.018904 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	495	Shared Neighborhood Hits	15
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.019964 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	480	Shared Neighborhood Hits	15
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

INSR_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.011366 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	963	Shared Neighborhood Hits	9
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

PCSK7_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.009967 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

COCA1_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.018339 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ROS_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.009739 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	907	Shared Neighborhood Hits	12
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SNPC2_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.019141 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

IBP1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.014215 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

LEPR_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.054015 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

SUSD2_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.011623 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

IL6RB_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.050379 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

INAR2_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.067342 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	P48551	Gene names	IFNAR2, IFNARB
Domain Architecture
Description	Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor 2).

Hits sorted by NC score

I10R2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

I10R2_MOUSE
NC score	0.968049 (rank : 2)	θ value	1.24909e-134 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

INAR1_HUMAN
NC score	0.680894 (rank : 3)	θ value	2.27762e-19 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

I20RA_HUMAN
NC score	0.676216 (rank : 4)	θ value	4.29542e-18 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

INGR2_HUMAN
NC score	0.675115 (rank : 5)	θ value	2.13179e-17 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	P38484, Q9BTL5	Gene names	IFNGR2, IFNGT1
Domain Architecture
Description	Interferon-gamma receptor beta chain precursor (Interferon-gamma receptor accessory factor 1) (AF-1) (Interferon-gamma transducer 1).

INAR1_MOUSE
NC score	0.657805 (rank : 6)	θ value	1.058e-16 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

I20RB_HUMAN
NC score	0.645454 (rank : 7)	θ value	7.84624e-12 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UXL0, Q6P438, Q8TAJ7	Gene names	IL20RB, DIRS1
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor beta chain precursor (IL-20R-beta) (IL-20R2).

I20RA_MOUSE
NC score	0.632123 (rank : 8)	θ value	1.29331e-14 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

I22RA_MOUSE
NC score	0.563547 (rank : 9)	θ value	2.61198e-07 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XF5, Q7TNI5	Gene names	Il22ra2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

I22RA_HUMAN
NC score	0.510407 (rank : 10)	θ value	3.19293e-05 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q969J5, Q6UWM1, Q96A41, Q96QR0	Gene names	IL22RA2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family class II member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

INGR1_HUMAN
NC score	0.403977 (rank : 11)	θ value	1.43324e-05 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P15260	Gene names	IFNGR1
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen) (CDw119).

TF_HUMAN
NC score	0.349282 (rank : 12)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P13726, Q6FHG2	Gene names	F3
Domain Architecture
Description	Tissue factor precursor (TF) (Coagulation factor III) (Thromboplastin) (CD142 antigen).

INGR1_MOUSE
NC score	0.339669 (rank : 13)	θ value	0.000602161 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

TF_MOUSE
NC score	0.301339 (rank : 14)	θ value	5.81887e-07 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P20352	Gene names	F3, Cf-3, Cf3
Domain Architecture
Description	Tissue factor precursor (TF) (Coagulation factor III) (CD142 antigen).

I28RA_HUMAN
NC score	0.292622 (rank : 15)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

I10R1_MOUSE
NC score	0.285417 (rank : 16)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q61727	Gene names	Il10ra, Il10r
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

I10R1_HUMAN
NC score	0.272390 (rank : 17)	θ value	0.00134147 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q13651	Gene names	IL10RA, IL10R
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

I28RA_MOUSE
NC score	0.259128 (rank : 18)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGK5, Q6PEV1	Gene names	Il28ra, Ifnlr1
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1).

IL3RB_HUMAN
NC score	0.203130 (rank : 19)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

IL3RB_MOUSE
NC score	0.181099 (rank : 20)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL3B2_MOUSE
NC score	0.164091 (rank : 21)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	372	Shared Neighborhood Hits	16
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL27B_MOUSE
NC score	0.116486 (rank : 22)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

IL21R_MOUSE
NC score	0.103701 (rank : 23)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL21R_HUMAN
NC score	0.086618 (rank : 24)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL5RA_MOUSE
NC score	0.074399 (rank : 25)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

INAR2_HUMAN
NC score	0.067342 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	P48551	Gene names	IFNAR2, IFNARB
Domain Architecture
Description	Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor 2).

SUSD3_HUMAN
NC score	0.063140 (rank : 27)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

LEPR_HUMAN
NC score	0.054015 (rank : 28)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

LEPR_MOUSE
NC score	0.052201 (rank : 29)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

IL6RB_HUMAN
NC score	0.050379 (rank : 30)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

I27RA_MOUSE
NC score	0.026080 (rank : 31)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

SDK2_MOUSE
NC score	0.019964 (rank : 32)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	480	Shared Neighborhood Hits	15
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

EPHA2_HUMAN
NC score	0.019142 (rank : 33)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	1021	Shared Neighborhood Hits	20
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

SNPC2_HUMAN
NC score	0.019141 (rank : 34)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

SDK2_HUMAN
NC score	0.018904 (rank : 35)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	495	Shared Neighborhood Hits	15
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

USH2A_MOUSE
NC score	0.018835 (rank : 36)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	626	Shared Neighborhood Hits	14
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

COCA1_HUMAN
NC score	0.018339 (rank : 37)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CNTN3_MOUSE
NC score	0.016913 (rank : 38)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

EPHA2_MOUSE
NC score	0.016358 (rank : 39)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	1020	Shared Neighborhood Hits	18
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

IBP1_MOUSE
NC score	0.014215 (rank : 40)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

INSR_MOUSE
NC score	0.013784 (rank : 41)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	968	Shared Neighborhood Hits	9
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SUSD2_MOUSE
NC score	0.011623 (rank : 42)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

INSR_HUMAN
NC score	0.011366 (rank : 43)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	963	Shared Neighborhood Hits	9
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

PCSK7_MOUSE
NC score	0.009967 (rank : 44)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

ROS_HUMAN
NC score	0.009739 (rank : 45)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	907	Shared Neighborhood Hits	12
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).