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Network neighborhood for query Sequence : HPSE2_HUMAN

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HPSE2_HUMAN
SwissProt Accessions	Q8WWQ2, Q5VUH4, Q5VUH5, Q5VUH6, Q8WWQ1, Q9HB37, Q9HB38, Q9HB39	Gene names	HPSE2, HPA2
Domain Architecture	No domain graphic available
Description	Heparanase-2 (EC 3.2.-.-) (Hpa2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HPSE2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ2, Q5VUH4, Q5VUH5, Q5VUH6, Q8WWQ1, Q9HB37, Q9HB38, Q9HB39	Gene names	HPSE2, HPA2
Domain Architecture	No domain graphic available
Description	Heparanase-2 (EC 3.2.-.-) (Hpa2).

HPSE_MOUSE
θ value	4.30305e-127 (rank : 2)	NC score	0.970867 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q6YGZ1, Q8K3K3	Gene names	Hpse, Hpa
Domain Architecture	No domain graphic available
Description	Heparanase precursor (EC 3.2.-.-) (Endo-glucoronidase) [Contains: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit].

HPSE_HUMAN
θ value	2.44341e-122 (rank : 3)	NC score	0.969006 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y251, Q53GE5, Q9UL39	Gene names	HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1
Domain Architecture	No domain graphic available
Description	Heparanase precursor (EC 3.2.-.-) (Heparanase-1) (Hpa1) (Endo- glucoronidase) [Contains: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit].

ENW1_HUMAN
θ value	4.03905 (rank : 4)	NC score	0.021995 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

CDC27_HUMAN
θ value	8.99809 (rank : 5)	NC score	0.012437 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

NELFA_MOUSE
θ value	8.99809 (rank : 6)	NC score	0.013490 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	195	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PCDG1_HUMAN
θ value	8.99809 (rank : 7)	NC score	0.002067 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H4, Q9Y5D6	Gene names	PCDHGA1
Domain Architecture
Description	Protocadherin gamma A1 precursor (PCDH-gamma-A1).

TAP2_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.004890 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

Hits sorted by NC score

HPSE2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ2, Q5VUH4, Q5VUH5, Q5VUH6, Q8WWQ1, Q9HB37, Q9HB38, Q9HB39	Gene names	HPSE2, HPA2
Domain Architecture	No domain graphic available
Description	Heparanase-2 (EC 3.2.-.-) (Hpa2).

HPSE_MOUSE
NC score	0.970867 (rank : 2)	θ value	4.30305e-127 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q6YGZ1, Q8K3K3	Gene names	Hpse, Hpa
Domain Architecture	No domain graphic available
Description	Heparanase precursor (EC 3.2.-.-) (Endo-glucoronidase) [Contains: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit].

HPSE_HUMAN
NC score	0.969006 (rank : 3)	θ value	2.44341e-122 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y251, Q53GE5, Q9UL39	Gene names	HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1
Domain Architecture	No domain graphic available
Description	Heparanase precursor (EC 3.2.-.-) (Heparanase-1) (Hpa1) (Endo- glucoronidase) [Contains: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit].

ENW1_HUMAN
NC score	0.021995 (rank : 4)	θ value	4.03905 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

NELFA_MOUSE
NC score	0.013490 (rank : 5)	θ value	8.99809 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	195	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

CDC27_HUMAN
NC score	0.012437 (rank : 6)	θ value	8.99809 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

TAP2_HUMAN
NC score	0.004890 (rank : 7)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

PCDG1_HUMAN
NC score	0.002067 (rank : 8)	θ value	8.99809 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H4, Q9Y5D6	Gene names	PCDHGA1
Domain Architecture
Description	Protocadherin gamma A1 precursor (PCDH-gamma-A1).