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Network neighborhood for query Sequence : GMDS_HUMAN

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GMDS_HUMAN
SwissProt Accessions	O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9	Gene names	GMDS
Domain Architecture
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GMDS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9	Gene names	GMDS
Domain Architecture
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

GMDS_MOUSE
θ value	0 (rank : 2)	NC score	0.999328 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0C9	Gene names	Gmds
Domain Architecture	No domain graphic available
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

TGDS_MOUSE
θ value	1.42992e-13 (rank : 3)	NC score	0.536383 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDR7	Gene names	Tgds
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

TGDS_HUMAN
θ value	6.00763e-12 (rank : 4)	NC score	0.523823 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	O95455, Q5T3Z2, Q9H1T9	Gene names	TGDS
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

UXS1_HUMAN
θ value	1.38499e-08 (rank : 5)	NC score	0.459898 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_MOUSE
θ value	1.38499e-08 (rank : 6)	NC score	0.460446 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

GALE_HUMAN
θ value	7.1131e-05 (rank : 7)	NC score	0.381702 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q14376, Q86W41, Q9BVE3, Q9UJB4	Gene names	GALE
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

GALE_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.366428 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R059	Gene names	Gale
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

M3K5_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.010333 (rank : 15)
Query Neighborhood Hits	13	Target Neighborhood Hits	867	Shared Neighborhood Hits	5
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K15_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.007310 (rank : 17)
Query Neighborhood Hits	13	Target Neighborhood Hits	914	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

TMIE_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.071710 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEW7	Gene names	TMIE
Domain Architecture	No domain graphic available
Description	Transmembrane inner ear expressed protein precursor.

TMIE_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.069387 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K467	Gene names	Tmie
Domain Architecture	No domain graphic available
Description	Transmembrane inner ear expressed protein precursor.

M3K5_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.008281 (rank : 16)
Query Neighborhood Hits	13	Target Neighborhood Hits	868	Shared Neighborhood Hits	5
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

FCL_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.135072 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q13630, Q567Q9, Q9UDG7	Gene names	TSTA3
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).

FCL_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.125227 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P23591	Gene names	Tsta3, P35b, Tstap35b
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).

NSDHL_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.090453 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q15738, O00344	Gene names	NSDHL, H105E3
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).

NSDHL_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.092973 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

Hits sorted by NC score

GMDS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9	Gene names	GMDS
Domain Architecture
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

GMDS_MOUSE
NC score	0.999328 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0C9	Gene names	Gmds
Domain Architecture	No domain graphic available
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

TGDS_MOUSE
NC score	0.536383 (rank : 3)	θ value	1.42992e-13 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDR7	Gene names	Tgds
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

TGDS_HUMAN
NC score	0.523823 (rank : 4)	θ value	6.00763e-12 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	O95455, Q5T3Z2, Q9H1T9	Gene names	TGDS
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

UXS1_MOUSE
NC score	0.460446 (rank : 5)	θ value	1.38499e-08 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_HUMAN
NC score	0.459898 (rank : 6)	θ value	1.38499e-08 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

GALE_HUMAN
NC score	0.381702 (rank : 7)	θ value	7.1131e-05 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q14376, Q86W41, Q9BVE3, Q9UJB4	Gene names	GALE
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

GALE_MOUSE
NC score	0.366428 (rank : 8)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R059	Gene names	Gale
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

FCL_HUMAN
NC score	0.135072 (rank : 9)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q13630, Q567Q9, Q9UDG7	Gene names	TSTA3
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).

FCL_MOUSE
NC score	0.125227 (rank : 10)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P23591	Gene names	Tsta3, P35b, Tstap35b
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).

NSDHL_MOUSE
NC score	0.092973 (rank : 11)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

NSDHL_HUMAN
NC score	0.090453 (rank : 12)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q15738, O00344	Gene names	NSDHL, H105E3
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).

TMIE_HUMAN
NC score	0.071710 (rank : 13)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEW7	Gene names	TMIE
Domain Architecture	No domain graphic available
Description	Transmembrane inner ear expressed protein precursor.

TMIE_MOUSE
NC score	0.069387 (rank : 14)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K467	Gene names	Tmie
Domain Architecture	No domain graphic available
Description	Transmembrane inner ear expressed protein precursor.

M3K5_MOUSE
NC score	0.010333 (rank : 15)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	867	Shared Neighborhood Hits	5
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K5_HUMAN
NC score	0.008281 (rank : 16)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	868	Shared Neighborhood Hits	5
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K15_HUMAN
NC score	0.007310 (rank : 17)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	914	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).