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Network neighborhood for query Sequence : ERG24_HUMAN

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ERG24_HUMAN
SwissProt Accessions	O76062, O95982, Q8IY06, Q96E64, Q96GZ1	Gene names	TM7SF2, ANG1
Domain Architecture
Description	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Delta14-SR) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR- 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERG24_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O76062, O95982, Q8IY06, Q96E64, Q96GZ1	Gene names	TM7SF2, ANG1
Domain Architecture
Description	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Delta14-SR) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR- 1).

LBR_HUMAN
θ value	7.07634e-138 (rank : 2)	NC score	0.979932 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

LBR_MOUSE
θ value	6.19918e-134 (rank : 3)	NC score	0.979936 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

DHCR7_HUMAN
θ value	1.71981e-67 (rank : 4)	NC score	0.927029 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBM7, O60492, O60717	Gene names	DHCR7, D7SR
Domain Architecture
Description	7-dehydrocholesterol reductase (EC 1.3.1.21) (7-DHC reductase) (Sterol delta-7-reductase) (Putative sterol reductase SR-2).

DHCR7_MOUSE
θ value	2.74572e-65 (rank : 5)	NC score	0.927742 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O88455	Gene names	Dhcr7
Domain Architecture
Description	7-dehydrocholesterol reductase (EC 1.3.1.21) (7-DHC reductase) (Sterol delta-7-reductase).

TLR13_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.018271 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

BRI3B_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.040243 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WY22, Q8WY23	Gene names	BRI3BP, KG19
Domain Architecture	No domain graphic available
Description	BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto- oncogene-binding protein KG19) (HCCR-1).

COKA1_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.009433 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	403	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KIT_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.005093 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.005179 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ICMT_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.030019 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O60725	Gene names	ICMT, PCCMT
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

KCNK6_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.008938 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

ICMT_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.025038 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQK7	Gene names	Icmt
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

Hits sorted by NC score

ERG24_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O76062, O95982, Q8IY06, Q96E64, Q96GZ1	Gene names	TM7SF2, ANG1
Domain Architecture
Description	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Delta14-SR) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR- 1).

LBR_MOUSE
NC score	0.979936 (rank : 2)	θ value	6.19918e-134 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

LBR_HUMAN
NC score	0.979932 (rank : 3)	θ value	7.07634e-138 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

DHCR7_MOUSE
NC score	0.927742 (rank : 4)	θ value	2.74572e-65 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O88455	Gene names	Dhcr7
Domain Architecture
Description	7-dehydrocholesterol reductase (EC 1.3.1.21) (7-DHC reductase) (Sterol delta-7-reductase).

DHCR7_HUMAN
NC score	0.927029 (rank : 5)	θ value	1.71981e-67 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBM7, O60492, O60717	Gene names	DHCR7, D7SR
Domain Architecture
Description	7-dehydrocholesterol reductase (EC 1.3.1.21) (7-DHC reductase) (Sterol delta-7-reductase) (Putative sterol reductase SR-2).

BRI3B_HUMAN
NC score	0.040243 (rank : 6)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WY22, Q8WY23	Gene names	BRI3BP, KG19
Domain Architecture	No domain graphic available
Description	BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto- oncogene-binding protein KG19) (HCCR-1).

ICMT_HUMAN
NC score	0.030019 (rank : 7)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O60725	Gene names	ICMT, PCCMT
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

ICMT_MOUSE
NC score	0.025038 (rank : 8)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQK7	Gene names	Icmt
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

TLR13_MOUSE
NC score	0.018271 (rank : 9)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

COKA1_HUMAN
NC score	0.009433 (rank : 10)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	403	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KCNK6_HUMAN
NC score	0.008938 (rank : 11)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KIT_MOUSE
NC score	0.005179 (rank : 12)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_HUMAN
NC score	0.005093 (rank : 13)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).