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Network neighborhood for query Sequence : ENOG_HUMAN

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ENOG_HUMAN
SwissProt Accessions	P09104, Q96J33	Gene names	ENO2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENOA_HUMAN
θ value	0 (rank : 1)	NC score	0.998950 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P06733, P22712, Q16704, Q4TUS4, Q658M5, Q6GMP2, Q71V37, Q7Z3V6, Q8WU71, Q9UM55	Gene names	ENO1, ENO1L1, MBPB1, MPB1
Domain Architecture
Description	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non- neural enolase) (NNE) (Enolase 1) (Phosphopyruvate hydratase) (C-myc promoter-binding protein) (MBP-1) (MPB-1) (Plasminogen-binding protein).

ENOA_MOUSE
θ value	0 (rank : 2)	NC score	0.998977 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P17182, Q99KT7, Q9DCY7	Gene names	Eno1, Eno-1
Domain Architecture
Description	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non- neural enolase) (NNE) (Enolase 1).

ENOB_HUMAN
θ value	0 (rank : 3)	NC score	0.999033 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	P13929, Q96AE2	Gene names	ENO3
Domain Architecture
Description	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) (Enolase 3).

ENOB_MOUSE
θ value	0 (rank : 4)	NC score	0.999066 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P21550	Gene names	Eno3, Eno-3
Domain Architecture
Description	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) (Enolase 3).

ENOG_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P09104, Q96J33	Gene names	ENO2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ENOG_MOUSE
θ value	0 (rank : 6)	NC score	0.999736 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	P17183	Gene names	Eno2, Eno-2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ENO1B_HUMAN
θ value	1.50581e-180 (rank : 7)	NC score	0.997435 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q05524	Gene names	ENO1B
Domain Architecture
Description	Alpha-enolase, lung specific (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (HLE1).

AKT3_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.002028 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.002028 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

ABCF2_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.008138 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

IOD1_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.011142 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P49895, Q1RN02, Q6Q4C1, Q6Q4C2, Q6Q4C3, Q6Q4C4, Q6Q4C5, Q6Q4C6, Q6Q4C7, Q6Q4C9, Q8WWC6	Gene names	DIO1, ITDI1, TXDI1
Domain Architecture
Description	Type I iodothyronine deiodinase (EC 1.97.1.10) (Type-I 5' deiodinase) (DIOI) (Type 1 DI) (5DI).

CPVL_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.017207 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

CRAC1_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.028326 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

SN1L1_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.001669 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	895	Shared Neighborhood Hits	5
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

CRAC1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.029472 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

Hits sorted by NC score

ENOG_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P09104, Q96J33	Gene names	ENO2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ENOG_MOUSE
NC score	0.999736 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	P17183	Gene names	Eno2, Eno-2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ENOB_MOUSE
NC score	0.999066 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P21550	Gene names	Eno3, Eno-3
Domain Architecture
Description	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) (Enolase 3).

ENOB_HUMAN
NC score	0.999033 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	P13929, Q96AE2	Gene names	ENO3
Domain Architecture
Description	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) (Enolase 3).

ENOA_MOUSE
NC score	0.998977 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P17182, Q99KT7, Q9DCY7	Gene names	Eno1, Eno-1
Domain Architecture
Description	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non- neural enolase) (NNE) (Enolase 1).

ENOA_HUMAN
NC score	0.998950 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P06733, P22712, Q16704, Q4TUS4, Q658M5, Q6GMP2, Q71V37, Q7Z3V6, Q8WU71, Q9UM55	Gene names	ENO1, ENO1L1, MBPB1, MPB1
Domain Architecture
Description	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non- neural enolase) (NNE) (Enolase 1) (Phosphopyruvate hydratase) (C-myc promoter-binding protein) (MBP-1) (MPB-1) (Plasminogen-binding protein).

ENO1B_HUMAN
NC score	0.997435 (rank : 7)	θ value	1.50581e-180 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q05524	Gene names	ENO1B
Domain Architecture
Description	Alpha-enolase, lung specific (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (HLE1).

CRAC1_HUMAN
NC score	0.029472 (rank : 8)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
NC score	0.028326 (rank : 9)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CPVL_HUMAN
NC score	0.017207 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

IOD1_HUMAN
NC score	0.011142 (rank : 11)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P49895, Q1RN02, Q6Q4C1, Q6Q4C2, Q6Q4C3, Q6Q4C4, Q6Q4C5, Q6Q4C6, Q6Q4C7, Q6Q4C9, Q8WWC6	Gene names	DIO1, ITDI1, TXDI1
Domain Architecture
Description	Type I iodothyronine deiodinase (EC 1.97.1.10) (Type-I 5' deiodinase) (DIOI) (Type 1 DI) (5DI).

ABCF2_HUMAN
NC score	0.008138 (rank : 12)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

AKT3_HUMAN
NC score	0.002028 (rank : 13)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
NC score	0.002028 (rank : 14)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

SN1L1_MOUSE
NC score	0.001669 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	895	Shared Neighborhood Hits	5
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).