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Network neighborhood for query Sequence : EFNB2_HUMAN

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EFNB2_HUMAN
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EFNB2_HUMAN
θ value	3.04115e-173 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

EFNB2_MOUSE
θ value	1.11932e-167 (rank : 2)	NC score	0.998937 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P52800	Gene names	Efnb2, Elf2, Epl5, Eplg5, Htkl, Lerk5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) (ELF-2).

EFNB1_HUMAN
θ value	1.44917e-82 (rank : 3)	NC score	0.976173 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P98172	Gene names	EFNB1, EFL-3, EPLG2, LERK2
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L).

EFNB1_MOUSE
θ value	4.66183e-81 (rank : 4)	NC score	0.974634 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P52795	Gene names	Efnb1, Epl2, Eplg2, Lerk2, Stra1
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L) (STRA1 protein) (CEK5 receptor ligand) (CEK5-L).

EFNB3_MOUSE
θ value	4.10295e-61 (rank : 5)	NC score	0.950978 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	O35393	Gene names	Efnb3
Domain Architecture
Description	Ephrin-B3 precursor.

EFNB3_HUMAN
θ value	1.19377e-60 (rank : 6)	NC score	0.946962 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

EFNA1_MOUSE
θ value	7.84624e-12 (rank : 7)	NC score	0.666445 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P52793, P97331	Gene names	Efna1, Epgl1, Epl1, Lerk1
Domain Architecture
Description	Ephrin-A1 precursor (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61).

EFNA1_HUMAN
θ value	8.67504e-11 (rank : 8)	NC score	0.654846 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P20827, Q5SR60, Q5SR61, Q6I9T9, Q8N578	Gene names	EFNA1, EPGL1, LERK1, TNFAIP4
Domain Architecture
Description	Ephrin-A1 precursor (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor, alpha-induced protein 4).

EFNA4_MOUSE
θ value	1.25267e-09 (rank : 9)	NC score	0.605847 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	O08542, O55218	Gene names	Efna4, Epl4, Eplg4, Lerk4
Domain Architecture
Description	Ephrin-A4 precursor (EPH-related receptor tyrosine kinase ligand 4) (LERK-4).

EFNA3_HUMAN
θ value	2.13673e-09 (rank : 10)	NC score	0.623470 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P52797, Q5SR70	Gene names	EFNA3, EFL2, EPLG3, LERK3
Domain Architecture
Description	Ephrin-A3 precursor (EPH-related receptor tyrosine kinase ligand 3) (LERK-3) (EHK1 ligand) (EHK1-L) (EFL-2).

EFNA5_HUMAN
θ value	2.79066e-09 (rank : 11)	NC score	0.601509 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P52803	Gene names	EFNA5, EPLG7, LERK7
Domain Architecture
Description	Ephrin-A5 precursor (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) (AL-1).

EFNA5_MOUSE
θ value	2.79066e-09 (rank : 12)	NC score	0.600493 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	O08543, O08544	Gene names	Efna5, Epl7, Eplg7, Lerk7
Domain Architecture
Description	Ephrin-A5 precursor (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) (AL-1).

EFNA2_HUMAN
θ value	6.21693e-09 (rank : 13)	NC score	0.620817 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	O43921, O76020	Gene names	EFNA2, EPLG6, LERK6
Domain Architecture
Description	Ephrin-A2 precursor (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (HEK7-ligand) (HEK7-L).

EFNA4_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.614805 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P52798, O95457	Gene names	EFNA4, EPLG4, LERK4
Domain Architecture
Description	Ephrin-A4 precursor (EPH-related receptor tyrosine kinase ligand 4) (LERK-4).

EFNA2_MOUSE
θ value	1.80886e-08 (rank : 15)	NC score	0.615112 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P52801	Gene names	Efna2, Elf1, Epl6, Eplg6, Lerk6
Domain Architecture
Description	Ephrin-A2 precursor (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (ELF-1) (CEK7-ligand) (CEK7-L).

S38A4_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.045895 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q969I6	Gene names	SLC38A4, ATA3, NAT3, SNAT4
Domain Architecture	No domain graphic available
Description	Sodium-coupled neutral amino acid transporter 4 (Na(+)-coupled neutral amino acid transporter 4) (Amino acid transporter A3) (System A amino acid transporter 3) (System N amino acid transporter 3) (Solute carrier family 38 member 4).

S38A4_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.046908 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1S9, Q3TEZ9, Q3TJ89, Q3TPL5, Q8VIE7	Gene names	Slc38a4, Ata3, Nat3, Snat4
Domain Architecture	No domain graphic available
Description	Sodium-coupled neutral amino acid transporter 4 (Na(+)-coupled neutral amino acid transporter 4) (Amino acid transporter A3) (System A amino acid transporter 3) (Solute carrier family 38 member 4).

ANKS6_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.010272 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

RHG05_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.014613 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SLC31_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.019675 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q07837, O00658, Q15295	Gene names	SLC3A1, RBAT
Domain Architecture
Description	Neutral and basic amino acid transport protein rBAT (B(0,+)-type amino acid transport protein) (NBAT) (D2H).

SP1_HUMAN
θ value	6.88961 (rank : 21)	NC score	-0.000803 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	722	Shared Neighborhood Hits	2
SwissProt Accessions	P08047, Q86TN8, Q9H3Q5, Q9NR51, Q9NY21, Q9NYE7	Gene names	SP1, TSFP1
Domain Architecture
Description	Transcription factor Sp1.

UNC5C_MOUSE
θ value	6.88961 (rank : 22)	NC score	0.006145 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

CALR_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.006697 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CC018_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.014454 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK00	Gene names	C3orf18
Domain Architecture	No domain graphic available
Description	Protein C3orf18 (Protein G20).

Hits sorted by NC score

EFNB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.04115e-173 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

EFNB2_MOUSE
NC score	0.998937 (rank : 2)	θ value	1.11932e-167 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P52800	Gene names	Efnb2, Elf2, Epl5, Eplg5, Htkl, Lerk5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) (ELF-2).

EFNB1_HUMAN
NC score	0.976173 (rank : 3)	θ value	1.44917e-82 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P98172	Gene names	EFNB1, EFL-3, EPLG2, LERK2
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L).

EFNB1_MOUSE
NC score	0.974634 (rank : 4)	θ value	4.66183e-81 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P52795	Gene names	Efnb1, Epl2, Eplg2, Lerk2, Stra1
Domain Architecture
Description	Ephrin-B1 precursor (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (ELK ligand) (ELK-L) (STRA1 protein) (CEK5 receptor ligand) (CEK5-L).

EFNB3_MOUSE
NC score	0.950978 (rank : 5)	θ value	4.10295e-61 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	O35393	Gene names	Efnb3
Domain Architecture
Description	Ephrin-B3 precursor.

EFNB3_HUMAN
NC score	0.946962 (rank : 6)	θ value	1.19377e-60 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

EFNA1_MOUSE
NC score	0.666445 (rank : 7)	θ value	7.84624e-12 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P52793, P97331	Gene names	Efna1, Epgl1, Epl1, Lerk1
Domain Architecture
Description	Ephrin-A1 precursor (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61).

EFNA1_HUMAN
NC score	0.654846 (rank : 8)	θ value	8.67504e-11 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P20827, Q5SR60, Q5SR61, Q6I9T9, Q8N578	Gene names	EFNA1, EPGL1, LERK1, TNFAIP4
Domain Architecture
Description	Ephrin-A1 precursor (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor, alpha-induced protein 4).

EFNA3_HUMAN
NC score	0.623470 (rank : 9)	θ value	2.13673e-09 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P52797, Q5SR70	Gene names	EFNA3, EFL2, EPLG3, LERK3
Domain Architecture
Description	Ephrin-A3 precursor (EPH-related receptor tyrosine kinase ligand 3) (LERK-3) (EHK1 ligand) (EHK1-L) (EFL-2).

EFNA2_HUMAN
NC score	0.620817 (rank : 10)	θ value	6.21693e-09 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	O43921, O76020	Gene names	EFNA2, EPLG6, LERK6
Domain Architecture
Description	Ephrin-A2 precursor (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (HEK7-ligand) (HEK7-L).

EFNA2_MOUSE
NC score	0.615112 (rank : 11)	θ value	1.80886e-08 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P52801	Gene names	Efna2, Elf1, Epl6, Eplg6, Lerk6
Domain Architecture
Description	Ephrin-A2 precursor (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (ELF-1) (CEK7-ligand) (CEK7-L).

EFNA4_HUMAN
NC score	0.614805 (rank : 12)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P52798, O95457	Gene names	EFNA4, EPLG4, LERK4
Domain Architecture
Description	Ephrin-A4 precursor (EPH-related receptor tyrosine kinase ligand 4) (LERK-4).

EFNA4_MOUSE
NC score	0.605847 (rank : 13)	θ value	1.25267e-09 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	O08542, O55218	Gene names	Efna4, Epl4, Eplg4, Lerk4
Domain Architecture
Description	Ephrin-A4 precursor (EPH-related receptor tyrosine kinase ligand 4) (LERK-4).

EFNA5_HUMAN
NC score	0.601509 (rank : 14)	θ value	2.79066e-09 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P52803	Gene names	EFNA5, EPLG7, LERK7
Domain Architecture
Description	Ephrin-A5 precursor (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) (AL-1).

EFNA5_MOUSE
NC score	0.600493 (rank : 15)	θ value	2.79066e-09 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	O08543, O08544	Gene names	Efna5, Epl7, Eplg7, Lerk7
Domain Architecture
Description	Ephrin-A5 precursor (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) (AL-1).

S38A4_MOUSE
NC score	0.046908 (rank : 16)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1S9, Q3TEZ9, Q3TJ89, Q3TPL5, Q8VIE7	Gene names	Slc38a4, Ata3, Nat3, Snat4
Domain Architecture	No domain graphic available
Description	Sodium-coupled neutral amino acid transporter 4 (Na(+)-coupled neutral amino acid transporter 4) (Amino acid transporter A3) (System A amino acid transporter 3) (Solute carrier family 38 member 4).

S38A4_HUMAN
NC score	0.045895 (rank : 17)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q969I6	Gene names	SLC38A4, ATA3, NAT3, SNAT4
Domain Architecture	No domain graphic available
Description	Sodium-coupled neutral amino acid transporter 4 (Na(+)-coupled neutral amino acid transporter 4) (Amino acid transporter A3) (System A amino acid transporter 3) (System N amino acid transporter 3) (Solute carrier family 38 member 4).

SLC31_HUMAN
NC score	0.019675 (rank : 18)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q07837, O00658, Q15295	Gene names	SLC3A1, RBAT
Domain Architecture
Description	Neutral and basic amino acid transport protein rBAT (B(0,+)-type amino acid transport protein) (NBAT) (D2H).

RHG05_MOUSE
NC score	0.014613 (rank : 19)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CC018_HUMAN
NC score	0.014454 (rank : 20)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK00	Gene names	C3orf18
Domain Architecture	No domain graphic available
Description	Protein C3orf18 (Protein G20).

ANKS6_MOUSE
NC score	0.010272 (rank : 21)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CALR_MOUSE
NC score	0.006697 (rank : 22)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

UNC5C_MOUSE
NC score	0.006145 (rank : 23)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

SP1_HUMAN
NC score	-0.000803 (rank : 24)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	722	Shared Neighborhood Hits	2
SwissProt Accessions	P08047, Q86TN8, Q9H3Q5, Q9NR51, Q9NY21, Q9NYE7	Gene names	SP1, TSFP1
Domain Architecture
Description	Transcription factor Sp1.