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Network neighborhood for query Sequence : DBLOH_HUMAN

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DBLOH_HUMAN
SwissProt Accessions	Q9NR28, Q96LV0, Q9BT11, Q9HAV6	Gene names	DIABLO, SMAC
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DBLOH_HUMAN
θ value	2.88631e-123 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR28, Q96LV0, Q9BT11, Q9HAV6	Gene names	DIABLO, SMAC
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

DBLOH_MOUSE
θ value	8.15288e-110 (rank : 2)	NC score	0.980710 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIQ3, Q9CZD1, Q9DCD3	Gene names	Diablo, Smac
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

KRHB4_MOUSE
θ value	0.47712 (rank : 3)	NC score	0.056710 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

K2C1B_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.052099 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	542	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

KRHB4_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.056269 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

BRE1B_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.040940 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	1040	Shared Neighborhood Hits	13
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.044175 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	970	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

K2C4_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.051130 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	471	Shared Neighborhood Hits	17
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

KRHB6_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.044492 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	413	Shared Neighborhood Hits	14
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

RRBP1_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.030435 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1306	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

NFL_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.038499 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	666	Shared Neighborhood Hits	18
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFL_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.038155 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	695	Shared Neighborhood Hits	19
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

RRBP1_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.024409 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	1650	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

K2C1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.044016 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	624	Shared Neighborhood Hits	16
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

KMHN1_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.017956 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	950	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

UBP8_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.012288 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CENPF_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.018704 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1932	Shared Neighborhood Hits	19
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KRHB2_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.050807 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

RHG18_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.023731 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

K22O_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.043906 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	485	Shared Neighborhood Hits	19
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

OPTN_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.014292 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

Hits sorted by NC score

DBLOH_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.88631e-123 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR28, Q96LV0, Q9BT11, Q9HAV6	Gene names	DIABLO, SMAC
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

DBLOH_MOUSE
NC score	0.980710 (rank : 2)	θ value	8.15288e-110 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIQ3, Q9CZD1, Q9DCD3	Gene names	Diablo, Smac
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

KRHB4_MOUSE
NC score	0.056710 (rank : 3)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

KRHB4_HUMAN
NC score	0.056269 (rank : 4)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

K2C1B_HUMAN
NC score	0.052099 (rank : 5)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	542	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

K2C4_HUMAN
NC score	0.051130 (rank : 6)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	471	Shared Neighborhood Hits	17
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

KRHB2_HUMAN
NC score	0.050807 (rank : 7)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

KRHB6_MOUSE
NC score	0.044492 (rank : 8)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	413	Shared Neighborhood Hits	14
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

BRE1B_MOUSE
NC score	0.044175 (rank : 9)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	970	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

K2C1_HUMAN
NC score	0.044016 (rank : 10)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	624	Shared Neighborhood Hits	16
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

K22O_HUMAN
NC score	0.043906 (rank : 11)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	485	Shared Neighborhood Hits	19
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

BRE1B_HUMAN
NC score	0.040940 (rank : 12)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	1040	Shared Neighborhood Hits	13
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

NFL_HUMAN
NC score	0.038499 (rank : 13)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	666	Shared Neighborhood Hits	18
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFL_MOUSE
NC score	0.038155 (rank : 14)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	695	Shared Neighborhood Hits	19
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

RRBP1_HUMAN
NC score	0.030435 (rank : 15)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	1306	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
NC score	0.024409 (rank : 16)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	1650	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RHG18_HUMAN
NC score	0.023731 (rank : 17)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

CENPF_HUMAN
NC score	0.018704 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	1932	Shared Neighborhood Hits	19
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KMHN1_HUMAN
NC score	0.017956 (rank : 19)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	950	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

OPTN_MOUSE
NC score	0.014292 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

UBP8_HUMAN
NC score	0.012288 (rank : 21)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).