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Network neighborhood for query Sequence : AAKB2_HUMAN

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AAKB2_HUMAN
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AAKB2_HUMAN
θ value	1.24331e-150 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
θ value	1.57279e-145 (rank : 2)	NC score	0.999807 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB1_HUMAN
θ value	1.30465e-99 (rank : 3)	NC score	0.987204 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y478, Q9UBV0, Q9UE20, Q9UEX2, Q9Y6V8	Gene names	PRKAB1, AMPK
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-1 (AMPK beta-1 chain) (AMPKb).

AAKB1_MOUSE
θ value	4.19693e-98 (rank : 4)	NC score	0.986410 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R078, Q91YN6	Gene names	Prkab1
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-1 (AMPK beta-1 chain) (AMPKb).

TBX5_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.046314 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	0.163984 (rank : 6)	NC score	0.046305 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

ULK2_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.010329 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	943	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

ULK2_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.005909 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	979	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

SETD2_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.008689 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	412	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

TBX4_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.029903 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.029916 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

Hits sorted by NC score

AAKB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.24331e-150 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
NC score	0.999807 (rank : 2)	θ value	1.57279e-145 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB1_HUMAN
NC score	0.987204 (rank : 3)	θ value	1.30465e-99 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y478, Q9UBV0, Q9UE20, Q9UEX2, Q9Y6V8	Gene names	PRKAB1, AMPK
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-1 (AMPK beta-1 chain) (AMPKb).

AAKB1_MOUSE
NC score	0.986410 (rank : 4)	θ value	4.19693e-98 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R078, Q91YN6	Gene names	Prkab1
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-1 (AMPK beta-1 chain) (AMPKb).

TBX5_HUMAN
NC score	0.046314 (rank : 5)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
NC score	0.046305 (rank : 6)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX4_MOUSE
NC score	0.029916 (rank : 7)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_HUMAN
NC score	0.029903 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

ULK2_MOUSE
NC score	0.010329 (rank : 9)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	943	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

SETD2_HUMAN
NC score	0.008689 (rank : 10)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	412	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ULK2_HUMAN
NC score	0.005909 (rank : 11)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	979	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).